6a-beta-Aporphin-11-ol, 10-methoxy- R-(-)-阿波佐丁
CAS 641-36-1 MFCD00242650
化学结构图
SMILES:
化学属性
| Mol. Formula | C₁₈H₁₉NO₂ |
|---|---|
| Mol. Weight | 281.35 |
| Melting Point | 119 - 122ºC |
| Boiling Point | |
| Flash Point | - |
别名和识别编码
| Chemical Name | 6a-beta-Aporphin-11-ol, 10-methoxy- |
|---|---|
| Synonym | (-)-Apocodeine 4H-Dibenzo(de,g)quinolin-11-ol, 5,6,6a,7-tetrahydro-10-methoxy-6-methyl-, Apocodein Apocodeine R-(-)-Apocodeine |
| CAS Number | 641-36-1 |
| Beilstein Registry Number | 0032938 |
| Chemical Name Translation | R-(-)-阿波佐丁 |
| Canonical SMILES | - |
| MDL Number | - |
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安全信息
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme
Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948
Volume(issue)/page/year: -,589,1948TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Mammal - cat
DOSE/DURATION : 15 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme
Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948
Volume(issue)/page/year: -,589,1948TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 25 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme
Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948
Volume(issue)/page/year: -,589,1948
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