Benzyl alcohol,3,5-dihydroxy-alpha-(((p-hydroxy-alpha-methylphenethyl)amino)methyl)- 非诺特罗
CAS 13392-18-2 MFCD00242675
化学结构图
SMILES: Br.CC(CC1C=CC(O)=CC=1)NCC(O)C1C=C(O)C=C(O)C=1
化学属性
| Mol. Formula | C17H21NO4 |
|---|---|
| Mol. Weight | 303.39 |
别名和识别编码
| Chemical Name | Benzyl alcohol,3,5-dihydroxy-alpha-(((p-hydroxy-alpha-methylphenethyl)amino)methyl)- |
|---|---|
| MDL Number | MFCD00242675 |
| Chemical Name Translation | 非诺特罗 |
| Synonym | 1-(p-hydroxyphenyl)-2-((beta-hydroxy-beta-(3’,5’-dihydroxyphenyl))ethyl)amin AURORA KA-7877 3,5-Dihydroxy-α-[[(4-hydroxy-α-methylphenethyl)amino]methyl]benzyl alcohol 1,3-benzenediol,5-(1-hydroxy-2-((2-(4-hydroxyphenyl)-1-methylethyl)amino)eth 1-(3,5-dihydroxyphenyl)-1-hydroxy-2-[(4-hydroxyphenyl)isopropylamino]ethane FENOTEROL 1-(3,5-Dihydroxyphenyl)-1-hydroxy-2-[1-(4-hydroxyphenyl)isopropyl]aminoethane lcohol 5-[1-hydroxy-2-[[2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]-1,3-benzenediol benzylalcohol,3,5-dihydroxy-alpha-(((p-hydroxy-alpha-methylphenethyl)amino)me 1,3-Benzenediol, 5-[1-hydroxy-2-[[2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]- Benzyl alcohol, 3,5-dihydroxy-α-[[(p-hydroxy-α-methylphenethyl)amino]methyl]- (8CI) 1,3-Benzenediol, 1-(3,5-Dihydroxyphenyl)-2-(p-hydroxy-α-methylphenethylamino)ethanol 3,5-dihydroxy-alpha-(((p-hydroxy-alpha-methylphenethyl)amino)methyl)benzyla opropane Phenoterol 1-(3,5-Dihydroxyphenyl)-2-[[1-(4-hydroxybenzyl)ethyl]amino]ethanol Th 1165 3,5-Dihydroxy-α-[p-hydroxy-α-methylphenethylamino]methylbenzyl alcohol |
| CAS Number | 13392-18-2 |
| Wiswesser Line Notation | QR CQ EYQ1MY1&1R DQ |
| Beilstein Registry Number | 2157041 |
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相关文献及参考
- [2]. Wei Wang, et al. Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells. Biomed Pharmacother. 2016 Dec;84:185-190.
- [3]. Nada Choucair-Jaafar, et al. Beta2-adrenoceptor agonists alleviate neuropathic allodynia in mice after chronic treatment. Br J Pharmacol. 2009 Dec;158(7):1683-94.
- [4]. Amrita Datta, et al. High-throughput screening identified selective inhibitors of exosome biogenesis and secretion: A drug repurposing strategy for advanced cancer. Sci Rep. 2018 May 25;8(1):8161.
- [1]. R C Heel, et al. Fenoterol: a review of its pharmacological properties and therapeutic efficacy in asthma. Drugs. 1978 Jan;15(1):3-32.
- [1]. R C Heel, et al. Fenoterol: a review of its pharmacological properties and therapeutic efficacy in asthma. Drugs. 1978 Jan;15(1):3-32.
- [2]. Wei Wang, et al. Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibit
安全信息
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Multiple routes SPECIES OBSERVED : Human - woman DOSE : 576 ug/kg SEX/DURATION : female 34 week(s) after conception TOXIC EFFECTS : Reproductive - Effects on Newborn - biochemical and metabolic REFERENCE : JOPDAB Journal of Pediatrics. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1932- Volume(issue)/page/year: 94,449,1979
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rabbit DOSE : 562 ug/kg SEX/DURATION : female 27-29 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system REFERENCE : ARCGDG Archives of Gynecology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.226- 1978- Volume(issue)/page/year: 232,505,1981
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