MRT-10
CAS 330829-30-6 MFCD02734587
化学结构图
SMILES:
化学属性
| Mol. Weight | 465.52 |
|---|---|
| Mol. Formula | C24H23N3O5S |
别名和识别编码
| Synonym | N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide |
|---|---|
| MDL Number | MFCD02734587 |
| CAS Number | 330829-30-6 |
| Chemical Name | MRT-10 |
| PubChem Substance ID | 329825193 |
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分类
- {SNA} Angiogenic Factors, Bioactive Small Molecule Alphabetical Index, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, M, Sonic Hedgehog, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- Angiogenic Factors, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, M, Sonic Hedgehog
相关文献及参考
- Manetti F, Faure H, Roudaut H, Gorojankina T, Traiffort E, Schoenfelder A, et al., Virtual screening-based discovery and mechanistic characterization of the acylthiourea MRT-10 family as smoothened antagonists. Mol. Pharmacol. 4 , 658-65, (2010)
安全信息
GHS Symbol
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- P273 Avoid release to the environment. 避免释放到环境中。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
- H318 Causes serious eye damage 严重伤害眼睛
- S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S39 Wear eye/face protection 戴眼睛/面孔保护装置；
- R50 Very toxic to aquatic organisms 对水生生物极毒
- R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
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