2,5-Diaminotoluene 2,5-二氨基甲苯

CAS 95-70-5 MFCD00035779

化学结构图

95-70-5
SMILES: Cc1cc(N)ccc1N

化学属性

Mol. FormulaC7H10N2
Mol. Weight122
Melting Point61.0 to 65.0 deg-C
Boiling Point168°C/1mmHg(lit.)
Solubility溶于水、乙醇、乙醚、热苯。

别名和识别编码

Chemical Name2,5-Diaminotoluene
EC Number202-442-1
Synonym 甲苯-2,5-二胺 2-METHYL-BENZENE-1,4-DIAMINE C.I. 76042 2,5-tolylenediamine para-meta-tolylenediamine TOLUENE-2,5-DIAMINE para-toluylenediamine 4-Amino-2-methylaniline 2,5-二氨基甲苯 2-甲基对苯二胺 para-tolylenediamine 对甲苯二胺 4-Benzenediamine,2-methyl-1 p,m-Tolylenediamine 2-Methyl-1,4-benzenediamine c.i.76042 2-methyl-4-benzenediamine Toluylene-2,5-diamine 2-methyl-para-phenylenediamine 2,5-Diaminotoluene 2-Methyl-1,4-benzenediamine; Toluene-2,5-diamine 邻甲基对苯二胺 2-Methyl-p-phenylenediamine p-Toluylendiamine 1,4-benzenediamine,2-methyl p-Toluenediamine ci76042 2,5-DIAMINOTOLUENE 2-甲基-1,4-苯二胺 1,4-Benzenediamine, 2-methyl- 2-methyl-1,4-benzenediamine 2,5-甲苯二胺 para-toluenediamine 2,5-二氨基甲苯,甲苯-2,5-二胺
CAS Number95-70-5
MDL NumberMFCD00035779
Chemical Name Translation2,5-二氨基甲苯
Reaxys-RN774521
PubChem Substance ID253660584
Wiswesser Line NotationZR DZ B1
Beilstein Registry Number0774521
InChIInChI=1S/C7H10N2/c1-5-4-6(8)2-3-7(5)9/h2-4H,8-9H2,1H3
LabNetwork Molecule IDLN00337053
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安全信息

Packing GroupIII
Hazard Codes T,N
Hazard Class6.1
UN Number 2811
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S37 Wear suitable gloves 戴适当手套;
  • S24 Avoid contact with skin 避免皮肤接触;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
Risk Statements
  • R25 Toxic if swallowed 吞咽有毒
  • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
  • R20/21 Harmful by inhalation and in contact with skin 吸入及与皮肤接触有害
  • R51/53
RTECSXS9700000
GHS Symbol
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P308+P313
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P302+P350
  • P337+P313
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P304+P340+P312
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P305+P351+P338+P337+P313
  • P308+P311
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P301+P310+P330
  • P405 Store locked up. 上锁保管。
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
  • P302+P352+P312+P362+P364
Signal word
Warnings 危化品目录(2015) 危险化学品
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 102 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
   Skin and Appendages - hair
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 15,607,1977

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 3600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JIDHAN Journal of Industrial Hygiene.  (Cambridge, MA)  V.1-17, 1919-35. For
   publisher information, see AEHLAU.  Volume(issue)/page/year: 13,87,1931

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 222 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - other changes
REFERENCE :
   ZEPTAT Zeitschrift fuer Experimentelle Pathologie und Therapie.  (Berlin,
   Ger.)  V.1-22, 1905-21. For publisher information, see REXMAS.
   Volume(issue)/page/year: 17,59,1915

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 625 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ZEPTAT Zeitschrift fuer Experimentelle Pathologie und Therapie.  (Berlin,
   Ger.)  V.1-22, 1905-21. For publisher information, see REXMAS.
   Volume(issue)/page/year: 17,59,1915

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Rodent - hamster Liver
DOSE/DURATION           : 10 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 136,255,1984

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 100 ug/plate
REFERENCE :
   PNASA6 Proceedings of the National Academy of Sciences of the United States
   of America.  (National Academy of Sciences, Printing & Pub. Office, 2101
   Constitution Ave., Washington, DC 20418) V.1-    1915-
   Volume(issue)/page/year: 72,2423,1975

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 10 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 136,255,1984

其他信息

  • 方法一:由氨基偶氮甲苯经还原而制得。
  • Sigma Aldrich:95-70-5(sigmaaldrich)
  • 外观性质:无色结晶。
  • MOL 文件:95-70-5.mol
  • 上游原料:偶氮甲苯
  • 用途一:用于染发剂、皮革染料的合成
  • 用途二:用于制造染料等,并用作毛皮染料。
  • 下游产品:碱性红 2
  • MSDS 信息:2,5-二氨基甲苯(95-70-5).msds

系列性分类


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