Mephentermine Hydrochloride

CAS 3978-34-5 MFCD03978345

化学结构图

3978-34-5
SMILES: CNC(C)(C)Cc1ccccc1.Cl

化学属性

Mol. Weight199.75
Mol. FormulaC11H17N.ClH

别名和识别编码

CAS Number3978-34-5
Chemical NameBenzeneethanamine, N,alpha,alpha-trimethyl-,hydrochloride
Synonym Mephenteramine hydrochloride Phenethylamine, N,alpha,alpha-trimethyl-, hydrochloride N,alpha,alpha-Trimethylbenzeneethanamine hydrochloride ########
PubChem Substance ID199291
InChIInChI=1S/C11H17N.ClH/c1-11(2,12-3)9-10-7-5-4-6-8-10;/h4-8,12H,9H2,1-3H3;1H
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分类

  • Amines
  • Aromatics
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Mephentermine is an ?-adrenergic agonist. Mephentermine is used as an antihypotensive.

相关文献及参考

  • Cook, T., et al.: Anaesthesia, 55, 42 (2000),
  • Garcia-Garcia, A., et al.: J. Antimicrob. Chemother., 53, 65 (2004),
  • Duart, M., et al.: J. Med. Chem., 49, 3667 (2006),

安全信息

RTECSDA0348400 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Behavioral - Straub tail
   Gastrointestinal - changes in structure or function of salivary glands
   Skin and Appendages - hair
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   15,304,1969

系列性分类

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