8-(4-Chlorophenylthio)-guanosine 3',5'-cyclic monophosphorothioate, Rp Isomer triethylammonium salt

CAS 276696-61-8 MFCD04037247

化学结构图

276696-61-8
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化学属性

Mol. FormulaC16H15ClN5O6PS2· C6H15N
Mol. Weight605.07

别名和识别编码

Chemical Name8-(4-Chlorophenylthio)-guanosine 3',5'-cyclic monophosphorothioate, Rp Isomer triethylammonium salt
Synonym 8-(4-Chlorophenylthio)-guanosine 3',5'-cyclic monophosphorothioate, Rp Isomer triethylammonium salt Rp-8-CPT-cGMPS Rp-8-CPT-cGMPS Rp-8-[(4-Chlorophenyl)thio]-cGMPS triethylammonium salt Rp-8-[(4-Chlorophenyl)thio]-guanosine-cyclic 3',5'-hydrogen phosphorothioate triethylammonium salt Rp-8-[(4-Chlorophenyl)thio]-cGMPS triethylammonium salt Rp-8-[(4-Chlorophenyl)thio]-guanosine-cyclic 3′,5′-hydrogen phosphorothioate triethylammonium salt
MDL NumberMFCD04037247
CAS Number276696-61-8
PubChem Substance ID329775000
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分类

  • {SNA} Bioactive Small Molecule Alphabetical Index, C-CH, Cyclic Nucleotide Metabolism, Cyclic Nucleotides and Analogs, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, G Proteins and Cyclic Nucleotides, Kinase/Phosphatase Biology, P to Q, Protein Kinase G (PKG), Protein kinase G I alpha, Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 酶、抑制剂和底物
  • {SNA} Bioactive Small Molecules, Biochemicals and Reagents, C-CH, Cell Biology, Cell Signaling and Neuroscience, Cyclic Nucleotide Metabolism, C

相关文献及参考

  • Butt, E., et al., (Rp)-8-pCPT-cGMPS, a novel cGMP-dependent protein kinase inhibitor. Eur. J. Pharmacol. 269 , 265-268, (1994) 摘要
  • Mathes, C. and Thompson, S.H., The nitric oxide/cGMP pathway couples muscarinic receptors to the activation of Ca 2+ influx. J. Neurosci. 16 , 1702, (1996) 摘要
  • Pineda, et al., Nitric oxide and carbon monoxide activate locus coeruleus neurons through a cGMP-dependent protein kinase: Involvement of a nonselective cationic channel. J. Neurosci. 16 , 1389-1399, (1996) 摘要
  • Abd, Alla S., et al Eur. J. Biochem. 241 , 498, (1996) 摘要

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

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