Normethandrone 甲基诺龙

CAS 514-61-4 MFCD00051139

化学结构图

514-61-4
SMILES: C[C@@]12CC[C@H]3[C@@H]4CCC(=O)C=C4CC[C@@H]3[C@H]1CC[C@@]2(C)O |&1:1,4,5,14,15,18|

化学属性

Mol. FormulaC19H28O2
Mol. Weight288.47
Melting Point153-158 ºC

别名和识别编码

Chemical NameNormethandrone
CAS Number514-61-4
Synonym Normethandrone ######## 19-Nor-17-alpha-methyltestosterone 17a-methyl-19-nor-delta4-androsten-17b-ol-3-one 17-beta-hydroxy-17-alpha-methyl-estr-4-en-3-on 17a-Methyl-19-nor-delta4-androsten-17b-ol-3-one; 17b-Hydroxy-3-oxo-17a-methyl-estra-4-ene; 19-Normethisterone NORMETHANDROLONE methalutin 17-Methyl-19-nortestosterone 4-ESTREN-17-ALPHA-METHYL-17-BETA-OL-3-ONE 17-beta-hydroxy-17-methylestr-4-en-3-one Methylestrenolone 19-normethisterone 17-alpha-Methyl-17-beta-hydroxy-4-estren-3-one 17-beta-Hydroxy-17-methylestr-4-en-3-one metalutin 17-methyl-19-nortestosterone Methyloestrenolone Metalutin Methylnortestosterone NORMETHISTERONE 4-ESTREN-17A-METHYL-17BETA-OL-3-ONE 甲基诺龙 Normetandrone METHYLESTRENOLONE Methalutin 19-nor-17-alpha-methyltestosterone Orgasteron 17-ALPHA-METHYL-19-NORTESTOSTERONE 17-alpha-Methyl-19-nortestosterone Normethandrolone NORETHANDRONE 17-alpha-methyl-17-beta-hydroxy-4-estren-3-one 甲诺酮 METHYL-19-NORTESTOSTERONE, 17A- 17-HYDROXY-17-METHYLESTR-4-EN-3-ONE NORMETHANDRONE 17b-hydroxy-3-oxo-17a-methyl-estra-4-ene
MDL NumberMFCD00051139
EC Number208-183-0
Chemical Name Translation甲基诺龙
Wiswesser Line NotationL E5 B666 OV MUTJ E1 FQ F1
Beilstein Registry Number2622263
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分类

  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Steroids

产品应用

  • Androgen.

相关文献及参考

  • Matias, P., et al.: J. Biol. Chem., 275, 26164 (2000),

安全信息

RTECSKG8000000 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 20 mg/kg
SEX/DURATION            : female 6-9 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 15,

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 112 mg/kg
SEX/DURATION            : male 14 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
   ANYAA9 Annals of the New York Academy of Sciences.  (New York Academy of
   Sciences, 2 E. 63rd St., New York, NY 10021)  V.1-    1877-
   Volume(issue)/page/year: 71,500,1958

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 2 mg/kg
SEX/DURATION            : female 6-7 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 15,955,1978

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 20 mg/kg
SEX/DURATION            : female 6-7 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total n

其他信息

  • MOL 文件:514-61-4.mol

系列性分类

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