Benzilic acid, 2-(diethylamino)ethyl ester

CAS 302-40-9 MFCD00055933

化学结构图

302-40-9
SMILES:

化学属性

Mol. FormulaC20H25NO3
Mol. Weight327.46

别名和识别编码

Chemical NameBenzilic acid, 2-(diethylamino)ethyl ester
EC Number206-123-8
Synonym Benzeneacetic acid, alpha-hydroxy-alpha-phenyl-, 2-(diethylamino)ethyl Benactyzin Benactyzine 2-Diethylaminoethyl 2-hydroxy-2,2-diphenyl-acetate Benactizina
CAS Number302-40-9
Wiswesser Line NotationQXR&R&VO2N2&2
Beilstein Registry Number2156821
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安全信息

RTECSDD2480000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   111,293,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 159 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   RPTOAN Russian Pharmacology and Toxicology (English Translation).
   Translation of FATOAO.  (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
   UK)  V.30-    1967-  Volume(issue)/page/year: 32,311,1969

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Human
DOSE/DURATION           : 100 ug/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
REFERENCE :
   85IVAW "Possible Long-Term Health Effects of Short-Term Exposure to Chemical
   Agents," National Research Council, 3 vols., Washington, DC, National
   Academy Press, 1982-85  Volume(issue)/page/year: 1,L1,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 135 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD-A099-745

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - hamster
DOSE/DURATION           : 10 mg/kg
REFERENCE :
   ACNSAX Activitas Nervosa Superior.  (Avicenum, Malostranske nam. 28, Prague
   1, Czechoslovakia) V.1-    1959-  Volume(issue)/page/year: 17,253,1975

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