2-(4-((7-CHLORO-2-QUINOXALINYL)OXY)-PHENOXY)-PROPIONIC ACID

CAS N/A MFCD05861262

化学结构图

N/A
SMILES: CC(OC1C=CC(=CC=1)OC1C=NC2C=CC(Cl)=CC=2N=1)C(O)=O

化学属性

Mol. FormulaC17H12N2O4ClNa
Mol. Weight366.73

别名和识别编码

Chemical NameXK469
Synonym 2-(4-((7-Chloro-2-quinoxalinyl)oxy)­phenoxy)­propionic acid 2-(4-((7-Chloro-2-quinoxalinyl)oxy)­phenoxy)­propionic acid NSC 697887 NSC 697887
MDL NumberMFCD05861262
PubChem Substance ID24278776
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分类

  • {SNA} Antitumor Agents, Apoptosis and Cell Cycle, Bioactive Small Molecules, Biochemicals and Reagents, Cancer Research, Cell Biology, Cell Cycle Proteins and Antibodies, Cell Cycle Regulators, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, R to Z, Topoisomerase II-B, X
  • {SNA} Apoptosis and Cell Cycle, Bioactive Small Molecule Alphabetical Index, Cell Cycle Proteins, Antibodies and Reagents, Cell Cycle Regulators, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, R to Z, Topoisomerase II-B, X,

相关文献及参考

  • Gao, H., et al., XK469, a selective topoisomerase IIβ poison. Proc. Natl. Acad. Sci. U. S. A. 96 , 12168-12173, (1999) 摘要
  • Mensah-Osman, E.J., et al., 2-[4-(7-chloro-2-quinoxalinyloxy)phenoxy]-propionic acid (XK469), an inhibitor of topoisomerase (Topo IIβ), regulates Topo IIα and enhances Topo IIα-mediated cytotoxicity. Mol. Cancer Ther. 1 , 1321-1326, (2002)

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. X - Bioactive Small Molecules
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Inhibitors - Enzymes, Inhibitors, and Substrates
  5. Enzyme Inhibitors by Enzyme - Enzyme Inhibitors
  6. R to Z - Enzyme Inhibitors by Enzyme
  7. Topoisomerase II-B - R to Z
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Apoptosis and Cell Cycle - Cell Signaling and Neuroscience
  5. Cell Cycle Proteins and Antibodies - Apoptosis and Cell Cycle
  6. Cell Cycle Regulators - Cell Cycle Proteins and Antibodies

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