SU 9516 (Z)-3-((1H-咪唑-4-基)亚甲基)-5-甲氧基吲哚啉-2-酮
CAS 377090-84-1 MFCD05865243
化学结构图
SMILES: COC1=CC2/C(=C/C3=CNC=N3)/C(=O)NC=2C=C1
化学属性
| Mol. Formula | C13H11N3O2 |
|---|---|
| Mol. Weight | 241.25 |
别名和识别编码
| Chemical Name | SU 9516 |
|---|---|
| MDL Number | MFCD05865243 |
| PubChem Substance ID | 24278633 |
| CAS Number | 377090-84-1 |
| Chemical Name Translation | (Z)-3-((1H-咪唑-4-基)亚甲基)-5-甲氧基吲哚啉-2-酮 |
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分类
- {SA} A to C, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Cyclin Dependant Kinase 2, Cyclin-Dependent Kinase (CDK), Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Kinase/Phosphatase Biology, Protein Kinase Inhibitors, S, Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors
- {SNA} A to C, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Cyclin Dependant Kinase 2, Cyclin-Dependent Kinase (CDK), Enzyme Inhibitors,
相关文献及参考
- Yu, B., et al, SU9516, a cyclin-dependent kinase 2 inhibitor, promotes accumulation of high molecular weight E2F complexes in human colon carcinoma cells. Biochem. Pharmacol. 64 , 91-100, (2002) 摘要
- Lane, M.E., et al, . A novel cdk2-selective inhibitor, SU9516, induces apoptosis in colon carcinoma cells. Cancer Res. 61 , 6170-6177, (2001)
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