JTC 801

CAS 244218-51-7 MFCD06198707

化学结构图

244218-51-7
SMILES: Cl.CC1=CC(N)=C2C=C(C=CC2=N1)NC(=O)C1C=CC=CC=1COC1C=CC(CC)=CC=1

化学属性

Mol. FormulaC26H25N3O2· HCl
Mol. Weight447.96

别名和识别编码

Chemical NameJTC-801
Synonym N-(4-amino-2-methylquinolin-6-yl)-2-(4-ethylphenoxymethyl)benzamide hydrochloride
MDL NumberMFCD06198707
Chemical Name Translation
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Bioactive Small Molecules, Cell Biology, J
  • {SNA} Bioactive Small Molecule Alphabetical Index, J, 生物活性小分子, 细胞生物学

相关文献及参考

  • [2]. Koyama T, et al. Nociceptin receptor antagonist JTC-801 inhibits nitrous oxide-induced analgesia in mice. J Anesth. 2009;23(2):301-3.
  • [3]. Shinkai H, et al. 4-Aminoquinolines: novel nociceptin antagonists with analgesic activity. J Med Chem, 2000, 43(24), 4667-4677.
  • [4]. Zhang Y, et al. Nociceptin/orphanin FQ peptide receptor antagonist JTC-801 reverses pain and anxiety symptoms in a rat model of post-traumatic stress disorder. Br J Pharmacol. 2015 Jan;172(2):571-82.
  • [1]. Yamada H, et al. Pharmacological profiles of a novel opioid receptor-like1 (ORL(1)) receptor antagonist, JTC-801. Br J Pharmacol, 2002, 135(2), 323-332.
  • [1]. Yamada H, et al. Pharmacological profiles of a novel opioid receptor-like1 (ORL(1)) receptor antagonist, JTC-801. Br J Pharmacol, 2002, 135(2), 323-332.
  • [2]. Koyama T, et al. Nociceptin receptor antagonist JTC-801 inhibits nitrous oxide-induced analgesia in mice. J Anesth. 2009;23(2):301-3.
  • [3]. Sh

安全信息

GHS Symbol
Precautionary statements
  • P305+P351+P338
Hazard statements
  • H413 Maycauselonglastingharmfuleffectstoaquaticlife 可能对水生生物造成长期持续有害影响。
  • H319 Causes serious eye irritation 严重刺激眼睛
WGK Germany1
Signal word Warning
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
Hazard Codes Xi
Risk Statements
  • R36 Irritating to eyes 刺激眼睛

系列性分类


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