6-Aminonicotinamide 6-氨基烟酰胺

CAS 329-89-5 MFCD00006327

化学结构图

329-89-5
SMILES: NC(=O)c1ccc(N)nc1

化学属性

Mol. FormulaC6
Mol. Weight137
Melting Point245-248
TSCANo
Density1.323
Stability对光敏感

别名和识别编码

Chemical Name6-Aminonicotinamide
MDL NumberMFCD00006327
CAS Number329-89-5
Synonym 6-AN 6-amino-3-pyridinecarboxamid 6-Ana FDA 0121 6-amino-nicotinamid 3-Pyridinecarboxamide, 6-amino- 6-氨基维生素PP NSC 21206 6-Aminonicotinamide fda0121 U-8774 6-氨基烟酰胺 6-Aminonikotinsaeureamid
PubChem Substance ID87562482
EC Number206-349-7
Beilstein Registry Number22(3/4)6727
Alfabeta NameAMINONICOTINAMIDE 6-
Chemical Name Translation6-氨基烟酰胺
Reaxys-RN116042
Wiswesser Line NotationT6NJ BZ EVZ
LabNetwork Molecule IDLN00181157
InChIInChI=1S/C6H7N3O/c7-5-2-1-4(3-9-5)6(8)10/h1-3H,(H2,7,9)(H2,8,10)
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分类

  • {SNA} Building Blocks, C6, Chemical Synthesis, Heterocyclic Building Blocks, Pyridines

产品应用

  • 有机合成。

相关文献及参考

  • Beilstein:22(3/4)6727

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H301+H311+H331
  • H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
Personal Protective Equipment Eyeshields, Gloves, type P2 (EN 143) respirator cartridges
RTECSUS4550000
Precautionary statements
  • P308+P313
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P302+P350
  • P403+P233
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P304+P340+P311
  • P301+P310+P330
  • P302+P352+P312+P361+P364
  • P405 Store locked up. 上锁保管。
Signal word
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
Risk Statements
Hazard Codes T
Warnings IRRITANT
Hazard Class6.1
UN Number 1655 2811
Packing GroupIII
Storage condition 密封避光保存。
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 11 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
   Behavioral - muscle weakness
REFERENCE :
   CAXXA4 Canadian Patents.  (U.S. Patent and Trademark Office, Foreign
   Patents, Washington, DC 20231)  Volume(issue)/page/year: #1089763

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 320 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AECTCV Archives of Environmental Contamination and Toxicology.
   (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
   070944)  V.1-    1973-  Volume(issue)/page/year: 14,111,1985

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Ear) - change in acuity
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   33,320,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 35 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
   Behavioral - muscle weakness
REFERENCE :
   CAXXA4 Canadian Patents.  (U.S. Patent and Trademark Office, Foreign
   Patents, Washington, DC 20231)  Volume(issue)/page/year: #1089763

TYPE OF TEST            : Dominant lethal test
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 1 mg/kg
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   19,371,1971

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 19 mg/kg
SEX/DURATION            : female 10 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 29,101,1984

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 17 mg/kg
SEX/DURATION            : female 9 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunte

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rode

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 3060 ug/kg
SEX/DURATION            : female 6-14 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - extra-embryonic structures
   (e.g., placenta, umbilical cord)
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Specific Developmental Abnormalities - craniofacial
   (including nose and tongue)
REFERENCE :
   NTIS** National Technical Information Service.  (Springfiel

其他信息

  • Alfa Aesar:6-氨基烟酰胺,99% 6-Aminonicotinamide, 99%(329-89-5)
  • 急性毒性:腹腔-大鼠LD50: 11 毫克/公斤; 口服-小鼠LDL0: 320 毫克/公斤
  • Sigma Aldrich:329-89-5(sigmaaldrich)
  • 图谱信息:6-氨基烟酰胺(329-89-5)核磁图( 1 HNMR) 6-氨基烟酰胺(329-89-5)核磁图( 13 CNMR) 6-氨基烟酰胺(329-89-5)红外图谱(IR1) 6-氨基烟酰胺(329-89-5)质谱(MS) 6-氨基烟酰胺(329-89-5)红外图谱(IR2)
  • 外观性质:白色结晶性粉末。100ml水可溶0.3g,不溶于一般有机溶剂。有致畸可能性。熔点:245-248℃
  • 类别:农药
  • 毒性分级:高毒
  • TCI Shanghai:6-氨基烟酰胺 6-Aminonicotinamide,>;99.0%(T)(329-89-5)
  • 100ml水可溶0.3g,不溶于一般有机溶剂。有致畸可能性。
  • Hazard Note:Toxic
  • 6-氨基烟酰胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 A0986 6-氨基烟酰胺 6-Aminonicotinamide 5G 1660元 2014/06/02 A0986 6-氨基烟酰胺 6-Aminonicotinamide 1G 540元 2010/05/25 L06692 6-氨基烟酰胺, 99% 6-Aminonicotinamide, 99% 5g 1834元
  • 灭火剂:干粉、泡沫、砂土、二氧化碳, 雾状水
  • 储运特性:库房通风低温干燥
  • MOL 文件:329-89-5.mol
  • 可燃性危险特性:可燃;燃烧产生有毒氮氧化物烟雾

系列性分类


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