3,4-Diaminopyridine 3,4-二氨基吡啶

CAS 54-96-6 MFCD00006401

化学结构图

54-96-6
SMILES: Nc1ccncc1N

化学属性

Mol. FormulaC5H7N3
Mol. Weight109.13
Melting Point216-218°C
Density1.422
Flash Point240°C
TSCANo
Solubility24 G/L (20 ºC)
Boiling Point369.3°C at 760 mmHg

别名和识别编码

Chemical Name3,4-Diaminopyridine
CAS Number54-96-6
Alfabeta NameDIAMINOPYRIDINE 34-,
MDL NumberMFCD00006401
Synonym Amifampridine {LY} Amifampridine {} {LY} Amifampridine {} {} {LY} Amifampridine {} {} {} {LY} Amifampridine {} {} {} {} {LY} Amifampridine {} {} {} {} {} {LY} Amifampridine {} {} {} {} {} {} {LY} Amifampridine {} {} {} {} {} {} {} {LY} Amifampridine {} {} {} {} {} {} {} {} {LY} Amifampridine {} {} {} {} {} {} {} {} {} {LY} Amifampridine {} {} {} {} {} {} {} {} {} {} {LY} Amifampridine {} {} {} {} {} {} {} {} {} {} {} {LY} Amifampridine {} {} {} {} {} {} {} {} {} {} {} {} {LY} Amifampridine {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Amifampridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Amifampridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Amifampridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Amifampridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
EC Number200-220-9
Beilstein Registry Number110232
PubChem Substance ID5918
Merck Number2986
Chemical Name Translation3,4-二氨基吡啶
Reaxys-RN110232
Wiswesser Line NotationT6NJ CZ DZ
LabNetwork Molecule IDLN00007606
Canonical SMILESNC1=C(N)C=CN=C1
InChIInChI=1S/C5H7N3/c6-4-1-2-8-3-5(4)7/h1-3H,7H2,(H2,6,8)
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分类

  • {SNA} Building Blocks, C5, Chemical Synthesis, Heterocyclic Building Blocks, Pyridines

安全信息

Warnings IRRITANT, TOXIC
Signal word
GHS Symbol
WGK Germany3
Safety Statements
Risk Statements
  • R25 Toxic if swallowed 吞咽有毒
  • R26 Very toxic by inhalation 吸入极毒
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R21 Harmful in contact with skin 与皮肤接触有害
  • R36 Irritating to eyes 刺激眼睛
Precautionary statements
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P301+P310
  • P301+P316
  • P302+P350
  • P302+P352
  • P304+P340
  • P304+P340+P310
  • P305+P351+P338
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P316
  • P319
  • P320 Specific treatment is urgent (see … on this label). 紧急具体治疗(见本标签上的)。
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P322 Specific measures (see …on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P332+P313
  • P332+P317
  • P337+P313
  • P337+P317
  • P361 Remove/Take off immediately all contaminated clothing. 立即去除/脱掉所有被污染的衣服。
  • P361+P364
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P362+P364
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H300 Fatal if swallowed 吞食致命
  • H300+H330
  • H311 Toxic in contact with skin 皮肤接触中毒
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H330 Fatal if inhaled 吸入致命
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
RTECSUS7600000
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Packing GroupII
UN Number
Hazard Codes T+
Hazard Class6.1
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - wild bird species
DOSE/DURATION           : 75 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AECTCV Archives of Environmental Contamination and Toxicology.
   (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
   070944)  V.1-    1973-  Volume(issue)/page/year: 12,355,1983

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 35 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
   Skin and Appendages - hair
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 150,413,1964

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 13 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   APFRAD Annales Pharmaceutiques Francaises.  (SPPIF, B.P.22, F-41353 Vineuil,
   France)  V.1-    1943-  Volume(issue)/page/year: 26,345,1968

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 20 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volu

Storage condition 2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {

其他信息

  • 检测方法:HPLC
  • 图谱信息:3,4-二氨基吡啶(54-96-6)红外图谱(IR1) 3,4-二氨基吡啶(54-96-6)红外图谱(IR2)
  • MOL 文件:54-96-6.mol
  • Alfa Aesar:3,4-二氨基吡啶,98+% 3,4-Diaminopyridine, 98+%(54-96-6)
  • F:10-23
  • 上游原料:甲醇 --> 硝酸 --> 氢氧化铵 --> 钯 --> 发烟硫酸 --> 五氯化磷 --> 乙酸铵 --> 4-氨基-3-硝基吡啶 --> 4-羟基吡啶
  • 存储注意事项:光敏感;氮气保护
  • Sigma Aldrich:54-96-6(sigmaaldrich)
  • Hazard Note:Irritant
  • 海关编码:29333999
  • 3,4-二氨基吡啶价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 D1149 3,4-二氨基吡啶 3,4-Diaminopyridine 5G 1110元 2014/06/02 D1149 3,4-二氨基吡啶 3,4-Diaminopyridine 1G 331元 2010/06/21 112390250 3,4-二氨基吡啶 3,4-Diaminopyridine 98% 25 GR 5581元
  • 3,4-二氨基吡啶价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/04/16 D1149 3,4-二氨基吡啶 3,4-Diaminopyridine 5G 1260元 2011/04/16 D1149 3,4-二氨基吡啶 3,4-Diaminopyridine 1G 382元 2010/06/21 112390250 3,4-二氨基吡啶 3,4-Diaminopyridine 98% 25 GR 5581元
  • Acros Organics:3,4-二氨基吡啶 3,4-Diaminopyridine, 98%(54-96-6)
  • TCI Shanghai:3,4-二氨基吡啶 3,4-Diaminopyridine,>;99.0%(GC)(T)(54-96-6)
  • MSDS 信息:3,4-Diaminopyridine(54-96-6).msds

系列性分类


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