N-Acetyl-Asp-Glu-Val-Asp-al

CAS 169332-60-9 MFCD00671412

化学结构图

169332-60-9
SMILES: CC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C=O

化学属性

Mol. FormulaC20H30N4O11
Mol. Weight502.47

别名和识别编码

Chemical NameN-Acetyl-Asp-Glu-Val-Asp-al
Synonym Ac-DEVD-CHO N-Acetyl-Asp-Glu-Val-Asp-al
MDL NumberMFCD00671412
PubChem Substance ID24890193
CAS Number169332-60-9
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分类

  • {SNA} A to C,
  • {SA} A to C, A-AM, Aldehydes, Apoptosis Enzymes, Apoptosis and Cell Cycle, Application Index, Bioactive Small Molecules, Biochemicals and Reagents, Building Blocks, C13-C60, Carbonyl Compounds, Caspase 10, Caspase 3,

相关文献及参考

  • Nicholson, D.W., et al., Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 376 , 37-43, (1995) 摘要
  • Harvey, K.J., Commitment and effector phases of the physiological cell death pathway elucidated with respect to Bcl-2 caspase, and cyclin-dependent kinase activities. Mol. Cell. Biol. 18 , 2912-2922, (1998) 摘要
  • Takahashi, M., et al., Proteolytic activation of PKN by caspase-3 or related protease during apoptosis. Proc. Natl. Acad. Sci. U. S. A. 95 , 11566-11571, (1998) 摘要
  • Santoro, M.F., et al., Regulation of protein phosphatase 2A activity by caspase-3 during apoptosis. J. Biol. Chem. 273 , 13119-13128, (1998)
  • Margonin, N., Substrate and inhibitor specificity of interleukin-1β converting enzyme and related caspases. J. Biol. Chem. 272 , 7223, (1997)

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类


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