Quinolin-5-amine 5-氨基喹啉

CAS 611-34-7 MFCD00006797

化学结构图

611-34-7
SMILES: Nc1cccc2ncccc12

化学属性

Mol. FormulaC9H8N2
Mol. Weight144.17
Boiling Point310°C at 760 mmHg
Melting Point106-109°C
TSCANo
Density1.422
Stability对空气敏感
Flash Point310°C

别名和识别编码

Chemical NameQuinolin-5-amine
CAS Number611-34-7
Alfabeta NameQUINOLINYLAMINE 5--
MDL NumberMFCD00006797
Synonym Quinolin-5-amine {LY} Quinolin-5-amine {} {LY} Quinolin-5-amine {} {} {LY} Quinolin-5-amine {} {} {} {LY} Quinolin-5-amine {} {} {} {} {LY} Quinolin-5-amine {} {} {} {} {} {LY} Quinolin-5-amine {} {} {} {} {} {} {LY} Quinolin-5-amine {} {} {} {} {} {} {} {LY} Quinolin-5-amine {} {} {} {} {} {} {} {} {LY} Quinolin-5-amine {} {} {} {} {} {} {} {} {} {LY} Quinolin-5-amine {} {} {} {} {} {} {} {} {} {} {LY} Quinolin-5-amine {} {} {} {} {} {} {} {} {} {} {} {LY} Quinolin-5-amine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Quinolin-5-amine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Quinolin-5-amine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Quinolin-5-amine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Quinolin-5-amine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
PubChem Substance ID11911
EC Number210-266-1
Beilstein Registry Number114479
Reaxys-RN114479
Chemical Name Translation5-氨基喹啉
Wiswesser Line NotationT66 BNJ GZ
LabNetwork Molecule IDLN00008096
InChIInChI=1S/C9H8N2/c10-8-4-1-5-9-7(8)3-2-6-11-9/h1-6H,10H2
Canonical SMILESNC1=C2C=CC=NC2=CC=C1
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分类

  • Building Blocks, C8 to C10, Chemical Synthesis, Heterocyclic Building Blocks, Quinolines
  • {uni_hamburg} no charge; nitrogen heterocycle; carbocycle; aromatic; large ring; fused rings; 6ring; 10ring; 1fragment
  • {SA} Building Blocks, C8 to C10, Chemical Synthesis, Heterocyclic Building Blocks, Quinolines

产品应用

  • Intermediate in the preparation of P2X7 antagonists

相关文献及参考

  • Donnelly-Roberts, D., et al.: Neuropharmacol., 56, 223 (2009),
  • Beil. 22 ,V,10,297
  • FT-IR 2 (3), 3917:A / FT-IR 1 (2), 863:B / FT-NMR 1 (3), 436:C / IR-Spectra (2), 1212:C / IR-Spectra (3), 1390:G / RegBook 1 (2), 2621:A / Structure Index 1 , 413:D:5 / Vapor Phase 3 , 1571:A
  • Short: III/35D3 Title: Nuclear Magnetic Resonance (NMR) Data: Chemical Shifts for Carbon-13, Part 3: Heterocycles Author: Gupta, R.R.; Jain, M.; Lechner, M.D.; Mikhova, B.M. Editor: Gupta, R.R.; Lechner, M.D. Source: Landolt-Börnstein, New Series Volume: III/35D3 Year: 2007 Keyword: C-13; NMR; carbon-13; chemical shifts; coupling constants; heterocycles; nuclear magnetic resonance ISBN: 978-3-540-29731-4 ISBN: 3-540-29731-6 Internet Resource: DOI: 10.1007/978-3-540-47067-0 RefComment: VIII, 342 p., 1 illus., Hardcover RefComment: Written for Science and engineers in the fields of physics, chemistry and physical chemistry who inted to use NMR to study the structure and the binding of molecules Abstract: Nuclear Magnetic Resonance (NMR) is based on the fact that certain nuclei exhibit a magnetic moment, orient by a magnetic field, and absorb characteristic frequencies in the radiofrequency part of the spectrum. NMR is now a leading technique and a powerful tool for the investigation of the structure and interaction of molecules. The present Landolt-Börnstein volume III/35 Nuclear Magnetic Resonance (NMR) Data is therefore of major interest to all scientists and engineers who use NMR to study the structure and the binding of molecules. Volume III/35 "NMR-Data" is divided into several subvolumes and parts. Subvolume III/35A contains the nuclei B-11 and P-31, subvolume III/35B contains the nuclei F-19 and N-15, subvolume III/35C contains the nucleus H-1, subvolume III/35D contains the nucleus C-13, subvolume III/35E contains the nucleus O-17, and subvolume III/35G contains the nucleus Se-77. More nuclei are pl

安全信息

Warnings IRRITANT
GHS Symbol
WGK Germany3
Hazard Codes Xi
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
RTECSVA9625000
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P332+P313
  • P305+P351+P338+P337+P313
  • P302+P350
  • P337+P313
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
Signal word
Safety Statements
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
Risk Statements
  • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
Storage condition 2-8°C, protect from light {LY} 2-8°C, protect from light Air Sensitive {} {LY} 2-8°C, protect from light {} {} {LY} 2-8°C, protect from light {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from
Packing GroupIII
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
REFERENCE :
   CBCCT* "Summary Tables of Biological Tests," National Research Council
   Chemical-Biological Coordination Center.  (National Academy of Science
   Library, 2101 Constitution Ave., NW, Washington, DC 20418)
   Volume(issue)/page/year: 6,61,1954

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 umol/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 187,191,1987

TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 16 ug/well
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 3,429,1981

其他信息

  • MOL 文件:611-34-7.mol
  • 存储注意事项:空气敏感
  • 上游原料:氢氧化钠 --> 乙酸乙酯 --> 硫酸 --> 二氯甲烷 --> 石油醚 --> 氯化亚锡 --> 甘油 --> 碘化钠 --> 3-硝基苯胺
  • MSDS 信息:5-Aminoquinoline(611-34-7).msds
  • Alfa Aesar:5-氨基喹啉,99% 5-Aminoquinoline, 99%(611-34-7)
  • 图谱信息:5-氨基喹啉(611-34-7)红外图谱(IR2) 5-氨基喹啉(611-34-7)红外图谱(IR1) 5-氨基喹啉(611-34-7)核磁图( 1 HNMR) 5-氨基喹啉(611-34-7)核磁图( 13 CNMR) 5-氨基喹啉(611-34-7)质谱(MS)
  • Sigma Aldrich:611-34-7(sigmaaldrich)
  • 用途一:用作有机合成中间体
  • 敏感性:Air Sensitive
  • 5-氨基喹啉价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 A0959 5-氨基喹啉 5-Aminoquinoline 5G 1650元 2014/06/02 A0959 5-氨基喹啉 5-Aminoquinoline 10G 2940元 2010/06/21 104600010 5-氨基喹啉 5-Aminoquinoline 1 GR 706元
  • F:2-10
  • Acros Organics:5-Aminoquinoline(611-34-7)
  • 用途二:有机中间体。
  • 下游产品:5-氯喹啉
  • Hazard Note:Harmful/Irritant/Air Sensitive
  • TCI Shanghai:5-氨基喹啉 5-Aminoquinoline,>;97.0%(T)(611-34-7)

系列性分类


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