Cefoxitin Sodium 头孢西丁钠盐

CAS 33564-30-6 MFCD00079042

化学结构图

33564-30-6
SMILES: [Na+].CO[C@]1(NC(=O)CC2=CC=CS2)[C@H]2SCC(COC(N)=O)=C(C([O-])=O)N2C1=O

化学属性

Mol. FormulaC16H16N3NaO7S2
Mol. Weight449.43

别名和识别编码

Chemical NameCefoxitin Sodium
CAS Number33564-30-6
Synonym Cefoxotin sodium Mefoxitin Merxin 头孢西丁 钠盐 Monosodium cefoxitin ######## Mefoxin Cefoxitin sodium salt Cenomycin
MDL NumberMFCD00079042
PubChem Substance ID24892725
EC Number251-574-6
Chemical Name Translation头孢西丁钠盐
Wiswesser Line NotationT46 ANV ES GUTJ CO1 G1OVZ HVO CMV1- BT5SJ &-NA-
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分类

  • {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, C, CA - CG, Chemical Structure, Chromatography, Drugs & Metabolites, Drugs of Abuse, Forensic and Veterinary Standards, Neat Compounds, Others
  • Alphabetic, Analytical Standards, Analytical/Chromatography, C, CA - CG, Chemical Structure, Chromatography, Drugs & Metabolites, Drugs of Abuse, Forensic and Veterinary Standards, Neat Compounds, Others
  • {SNA} Additional Standards, Analytical Standards,

产品应用

  • Semi-synthetic antibiotic derived from Cephamycin C, possessing high resistance to ?-lactamase inactivation. An antibacterial.

相关文献及参考

  • Wallick, H., et al.: Antimicrob. Agents Chemother., 5, 25 (1974),
  • Brenner, G.S., et al.: Anal. Profiles Drug Subs., 11, 169 (1982),
  • Merck 14 ,1936

安全信息

RTECSXI0330500
GHS Symbol
WGK Germany3
Signal word Warning
Hazard statements
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
Hazard Codes Xn
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Packing GroupIII 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 9250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YKYUA6 Yakkyoku.  Pharmacy.  (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo,
   Japan)  V.1-    1950-  Volume(issue)/page/year: 31,629,1980

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 8580 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IYKEDH Iyakuhin Kenkyu.  Study of Medical Supplies.  (Nippon Koteisho
   Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan)  V.1- 1970- 
   Volume(issue)/page/year: 11,181,1980

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YAKUD5 Gekkan Yakuji.  Pharmaceuticals Monthly.  (Yakugyo Jihosha, Inaoka
   Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan)  V.1-   1959-
   Volume(issue)/page/year: 22,123,1980

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YKYUA6 Yakkyoku.  Pharmacy.  (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo,
   Japan)  V.1-    1950-  Volume(issue)/page/year: 31,629,19

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE

系列性分类

  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Chromatography - Analytical Standards
  4. Forensic and Veterinary Standards - Chromatography
  5. Drugs of Abuse - Forensic and Veterinary Standards
  6. Chemical Structure - Drugs of Abuse
  7. Others - Chemical Structure
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Alphabetic - Analytical Standards
  4. C - Alphabetic
  5. CA - CG - C

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