2-(propylamino)-N-(o-tolyl)propanamide hydrochloride 盐酸丙胺卡因

CAS 1786-81-8 MFCD00079279

化学结构图

1786-81-8
SMILES: CCCNC(C)C(=O)Nc1ccccc1C.Cl

化学属性

Mol. FormulaC13H21ClN2O
Mol. Weight257
TSCANo
Melting Point164-168

别名和识别编码

Chemical Name2-(propylamino)-N-(o-tolyl)propanamide hydrochloride
Synonym 2-(propylamino)-o-propionotoluidide hydrochloride PRILOCAINE HYDROCHLORIDE EPP N-(2-甲基苯基)-2-丙胺-丙酰胺 盐酸盐 alpha-Propylamine-2-methyl-propionanilide hydrochloride Prilocaine hydrochloride n-(2-methylphenyl)-2-(propylamino)-propanamidmonohydrochloride PRILOCAINE HYDROCHLORIDE MM(CRM STANDARD) alpha-propylamine-2-methyl-propionanilidehydrochloride PRILOCAINE HYDROCHLORIDE ASSAY STANDARD BP(CRM STANDARD) PRILOCAINE HYDROCHLORIDE USP
MDL NumberMFCD00079279
PubChem Substance ID92163
EC Number217-244-0
CAS Number1786-81-8
Merck Number7743
Chemical Name Translation盐酸丙胺卡因
Reaxys-RN6541935
Beilstein Registry Number6541935
Wiswesser Line Notation3MY1&VMR B1
InChIInChI=1S/C13H20N2O.ClH/c1-4-9-14-11(3)13(16)15-12-8-6-5-7-10(12)2;/h5-8,11,14H,4,9H2,1-3H3,(H,15,16);1H
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分类

  • {SNA} Bioactive Small Molecules, Cell Biology, Core Bioreagents, Enzyme Inhibitors, P, Pharmacopoeia, Pharmacopoeia A-Z, Research Essentials
  • {SNA} Analytical Standards, Analytical/Chromatography, Chromatography, EP Standards, EP Standards P - R, Pharmaceutical Standards, Pharmacopeia Standards
  • {SNA} Analytical Standards, Chromatography, EP Standards, EP Standards P - R, Pharmaceutical Standards, Pharmacopeia Standards, 分析/色谱

安全信息

WGK Germany3
RTECSUG5775000
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
GHS Symbol 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 56600 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,692,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 148 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,692,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 790 mg

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 30 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland,
   OH, Chemical Rubber Co., 1969  Volume(issue)/page/year: -,99,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 55 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,692,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intr

其他信息

  • Sigma Aldrich:1786-81-8(sigmaaldrich)
  • MOL 文件:1786-81-8.mol

系列性分类

  1. Application Areas 应用领域分类
  2. Drug Discovery 新药研发
  3. Pharmacopoeia 药典
  4. Pharmacopoeia A-Z - Pharmacopoeia
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. P - Bioactive Small Molecules
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Ion Channels - Cell Signaling and Neuroscience
  5. Voltage-gated Ion Channels - Ion Channels
  6. Monovalent Ion Channels - Voltage-gated Ion Channels
  7. Ion Pump Inhibitors - Monovalent Ion Channels

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