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分类

• {SNA} 3.1.x.x Acting on esters, 3.x.x.x Hydrolases, Analytical and Industrial Enzymes, Application Index, Biochemicals and Reagents, Butyrylcholinesterase (BChE), Pseudocholinesterase, Nonspecific Cholinesterase, E.C. 3.1.1.8, Cell Biology, Cholinesterase Enzymes, Cholinesterase and Organophosphate Detection Reagents, Clinical Chemistry, Enzyme Class Index, Enzymes for Diagnostic Kit Manufacturing, Enzymes, Inhibitors, and Substrates, General Metabolic Enzymes, General Metabolic Enzymes A-H, Metabolomics
• {SNA} 3.1.x.x Acting on esters, 3.x.x.x Hydrolases, Biochemicals and Reagents, Enzyme Class Index, Enzymes, Inhibitors, and Substrates, General Metabolic Enzymes,
• {SNA} 3.1.x.x Acting on esters,

产品应用

• Selective inhibition of BChE activity can be used in the detection of organophosphates.Its use in the treatment of organophosphate toxicity has been explored. It has been reported that the level of BChE in human blood correlates to the degree of protection against potentially toxic nerve agents.Cholinesterases have also been investigated for their role in Alzheimer’s disease.

相关文献及参考

• Merck 14 ,2208

安全信息

其他信息

• Butyrl Cholinesterase catalyzes the hydrolysis of a number of choline esters according to the following reaction:Acylcholine + H2O → choline + acid It is a tetrameric glycoprotein with four subunits of equal size, each having a molecular weight of 110 kDa. Butyryl cholinesterase hydrolyzes butyrylcholine four times more rapidly than acetylcholine. Unlike acetyl cholinesterase, it does not hydrolyze D-≥-methyl acetylcholine. It is inhibited by 10-5 M physostigmine, numerous organophosphate esters, the carbamate derivates and quaternary ammonium salts.
• Butyrl Cholinesterase catalyzes the hydrolysis of a number of choline esters according to the following reaction:Acylcholine + H2O → choline + acid