Pituitary adenylate cyclase-activating peptide-38 (human)

CAS 124123-15-5 MFCD00081800

化学结构图

124123-15-5
SMILES: CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1c[n]c[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(N)=O

化学属性

Mol. Weight4534.26

别名和识别编码

Synonym PACAP-38
MDL NumberMFCD00081800
CAS Number137061-48-4
InChIKeyUFTCZKMBJOPXDM-XXFCQBPRSA-N
Chemical NamePituitary adenylate cyclase-activating peptide-38 (human)
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分类

  • Adenylate Cyclase Activators, Adenylyl Cyclase Activators, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cyclic Nucleotide Metabolism, G Proteins and Cyclic Nucleotides, Miscellaneous Peptides, P, Peptides and Proteins, Peptides for Cell Biology, Vasoactive Intestinal Peptides
  • {SA} Adenylate Cyclase Activators, Adenylyl Cyclase Activators, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cyclic Nucleotide Metabolism, G Proteins and Cyclic Nucleotides, Miscellaneous Peptides, P, Peptides and Proteins, Peptides for Cell Biology,

相关文献及参考

  • Tornoe, K., et al., PACAP-(1-38) as neurotransmitter in the porcine adrenal glands. Am. J. Physiol. Endocrinol. Metab. 279 , E1413-E1425, (2000) 摘要
  • Kinhult, J., et al., Pituitary adenylate cyclase-activating peptide 38 a potent endogenously produced dilator of human airways. Eur. Respir. J. 15 , 243-247, (2000) 摘要
  • Lutz, E.M., et al., Domains determining agonist selectivity in chimaeric VIP2 (VPAC2)/PACAP (PAC1) receptors. Br. J. Pharmacol. 128 , 934-940, (1999) 摘要
  • Dickinson, T., et al., The role of VIP/PACAP receptor subtypes in spinal somatosensory processing in rats with an experimental peripheral mononeuropathy. Neuropharmacology 38 , 167-180, (1999) 摘要
  • Martinez-Fuentes, A.J., et al., Pituitary adenylate cyclase-activating polypeptide (PACAP) 38 and PACAP27 activate common and distinct intracellular signaling pathways to stimulate growth hormone secretion from porcine somatotropes. Endocrinology 139 , 5116-5124, (1998) 摘要
  • Yada, T., et al., Pituitary adenylate cyclase-activating polypeptide is an extraordinarily potent intra-pancreatic regulator of insulin secretion from islet βcells. J. Biol. Chem. 269 , 1290-1293, (1994) 摘要

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. G Proteins and Cyclic Nucleotides - Cell Signaling and Neuroscience
  5. Cyclic Nucleotide Metabolism - G Proteins and Cyclic Nucleotides
  6. Adenylyl Cyclase Activators - Cyclic Nucleotide Metabolism
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. G Proteins and Cyclic Nucleotides - Cell Signaling and Neuroscience
  5. Cyclic Nucleotide Metabolism - G Proteins and Cyclic Nucleotides
  6. Adenylyl Cyclase Activators - Cyclic Nucleotide Metabolism

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