JHW 007 Hydrochloride

CAS 202645-74-7 MFCD08276982

化学结构图

202645-74-7
SMILES: Cl.CCCCN1[C@@H]2C[C@H](C[C@H]1CC2)OC(C1C=CC(F)=CC=1)C1C=CC(F)=CC=1 |&1:6,8,10|

化学属性

Mol. FormulaC24H30ClF2NO
Mol. Weight421.95

别名和识别编码

Chemical NameJHW 007 Hydrochloride
CAS Number202645-74-7
Synonym (3-endo)-3-[Bis(4-fluorophenyl)methoxy]-8-butyl-8-azabicyclo[3.2.1]octane Hydrochloride endo-3-[Bis(4-fluorophenyl)methoxy]-8-butyl-8-Azabicyclo[3.2.1]octane Hydrochloride
Chemical Name Translation
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • Aromatics
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • JHW 007 is a dopamine uptake inhibitor; displays high affinity for the dopamine transporter (DAT) (Ki = 25 nM compared to 1330 and 1730 for NET and SERT respectively). Suppresses the effects of cocain

相关文献及参考

  • Kopajtic, et al.: J. Pharmacol. Exp. Ther., 335, 703 (2010),
  • Velaquez-Sanchez, et al.: Eur. Neuropsychopharmacol., 20, 501 (2010),

系列性分类

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