4-Acetamido-N-(2-Aminophenyl)Benzamide 4-乙酰氨基-N-(2’-氨基苯基)-苯甲酰胺
CAS 112522-64-2 MFCD00866266
化学结构图
SMILES: CC(=O)NC1C=CC(=CC=1)C(=O)NC1C=CC=CC=1N
化学属性
| Mol. Formula | C15H15N3O2 |
|---|---|
| Mol. Weight | 269.30 |
别名和识别编码
| Chemical Name | 4-Acetamido-N-(2-Aminophenyl)Benzamide |
|---|---|
| Synonym | 4-Acetylamino-N-(2′-aminophenyl)benzamide 4-Acetylamino-N-(2'-aminophenyl)benzamide 4-Acetylamino-N-(2'-aminophenyl)benzamide Acetyldinaline Tacedinaline Acetyldinaline CI-994 Tacedinaline |
| MDL Number | MFCD00866266 |
| CAS Number | 112522-64-2 |
| PubChem Substance ID | 160871335 |
| Chemical Name Translation | 4-乙酰氨基-N-(2’-氨基苯基)-苯甲酰胺 |
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分类
- {SNA} Benzamide Inhibitors, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules for Epigenetic Research, CI-CZ, Gene Regulation and Expression, Histone Deacetylase Inhibitors, RNA-Protein Translation Inhibitors, 分子生物学, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学,
相关文献及参考
- Hubeek, I., et al., CI-994 (N-acetyl-dinaline) in combination with conventional anti-cancer agents is effective against acute myeloid leukemia in vitro and in vivo. Oncol. Rep. 19 , 1517-1523, (2008) 摘要
- Gediya, L.K., et al., Improved synthesis of histone deacetylase inhibitors (HDIs) (MS-275 and CI-994) and inhibitory effects of HDIs alone or in combination with RAMBAs or retinoids on growth of human LNCaP prostate cancer cells and tumor xenografts. Bioorg. Med. Chem. 16 , 3352-3360, (2008)
安全信息
GHS Symbol
- P305+P351+P338
- H319 Causes serious eye irritation 严重刺激眼睛
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- R36 Irritating to eyes 刺激眼睛
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