1,3,5,2,4,6-Triazatriphosphorine,2,2,4,4,6-pentakis(1-aziridinyl)-2,2,4,4,6,6-hexahydro-6- (4-morpholinyl)-

CAS 37132-72-2 MFCD00866472

化学结构图

37132-72-2
SMILES: C1CN(CCO1)P1(N=P(N=P(N=1)(N1CC1)N1CC1)(N1CC1)N1CC1)N1CC1

化学属性

Mol. FormulaC14H28N9OP3
Mol. Weight431.42

别名和识别编码

Chemical Name1,3,5,2,4,6-Triazatriphosphorine,2,2,4,4,6-pentakis(1-aziridinyl)-2,2,4,4,6,6-hexahydro-6- (4-morpholinyl)-
Synonym 2,2,4,4,6-Pentaethylenimino-6-morpholino-cyclotriphosphazatrien Photrine Fotrin Photrin
CAS Number37132-72-2
Wiswesser Line NotationT6NPNPNPJ B- AT6N DOTJ& B- AT3NTJ& D- AT3NTJ& D-AT3NTJ& F- AT3NTJ& F- AT3NTJ
Beilstein Registry Number1057273
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安全信息

RTECSXX9470000 
TYPE OF TEST            : DNA inhibition
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 30 mg/kg
REFERENCE :
   IANBAM Izvestiya Akademii Nauk SSSR, Seriya Biologicheskaya.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  No.1-    1936-
   Volume(issue)/page/year: (6),816,1991

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Cells - not otherwise specified
DOSE/DURATION           : 9200 nmol/L
REFERENCE :
   SOGEBZ Soviet Genetics.  English translation of GNKAA5.  (Plenum Pub. Corp.,
   233 Spring St., New York, NY 10013)  V.2-    1966- Volume(issue)/page/year:
   18,210,1982

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 7 mg/kg
REFERENCE :
   BEBMAE Byulleten' Eksperimental'noi Biologii i Meditsiny.  Bulletin of
   Experimental Biology and Medicine.  For English translation, see BEXBAN.
   (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 102(7),76,1986

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 20 mg/L/1H
REFERENCE :
   SOGEBZ Soviet Genetics.  English translation of GNKAA5.  (Plenum Pub. Corp.,
   233 Spring St., New York, NY 10013)  V.2-    1966- Volume(issue)/page/year:
   12,1552,1976

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Mammal - pig
DOSE/DURATION           : 15 mg/kg
REFERENCE :
   CYGEDX Cytology and Genetics (English Translation).  Translation of TGANAK.
   (Allerton Press Inc., 150 Fifth Ave., New York, NY 10011)  V.8-    1974-
   Volume(issue)/page/year: 12(6),21,1978

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 11200 ug/kg
SEX/DURATION            : male 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   KHFZAN Khimiko-Farmatsevticheskii Zhurnal.  Chemical Pharmaceutical Journal.
    For English translation, see PCJOAU.  (V/O Mezhdunarodnaya Kniga, 113095
   Moscow, USSR)  V.1-    1967-  Volume(issue)/page/year: 10(9),11,1976

系列性分类

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