Carbamic acid, isopropyl-,1-(3-(p-fluorobenzoyl)propyl)piperid-4-yl ester

CAS 20977-50-8 MFCD00866697

化学结构图

20977-50-8
SMILES: CC(C)NC(=O)OC1CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1

化学属性

Mol. FormulaC19H27FN2O3
Mol. Weight350.48

别名和识别编码

Chemical NameCarbamic acid, isopropyl-,1-(3-(p-fluorobenzoyl)propyl)piperid-4-yl ester
Wiswesser Line NotationT6NTJ A3VR DF& DOVMY1&1
Synonym 1-(3-(4-Fluorobenzoyl)propyl)-4-piperidyl N-isopropylcarbamate AL-1021
CAS Number20977-50-8
Beilstein Registry Number1551021
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安全信息

RTECSFB3235000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,184,1972

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 2140 ug/kg
TOXIC EFFECTS :
   Behavioral - rigidity (including catalepsy)
   Cardiac - change in rate
   Vascular - BP lowering not characterized in autonomic section
REFERENCE :
   CTCEA9 Current Therapeutic Research, Clinical & Experimental.  (Therapeutic
   Research Press, Inc., POB 514, Tenafly, NJ 07670)  V.1-    1959-
   Volume(issue)/page/year: 11,779,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 265 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,184,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 44 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,184,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED

系列性分类


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