Olanzapine 奥氮平

CAS 132539-06-1 MFCD00866702

化学结构图

132539-06-1
SMILES: Cc1cc2c(s1)Nc1ccccc1N=C2N1CCN(C)CC1

化学属性

Mol. FormulaC17H20N4S
Mol. Weight312
Melting Point192-196

别名和识别编码

Chemical NameOlanzapine
Synonym 2-Methyl-4-(4-methyl-1-piperazinyl)- 10H-thieno[2,3-b][1,5]benzodiazepine LY-170053 2-​Methyl-​4-​(4-​methyl-​1-​piperazinyl)​-10H-​thieno[2,3-​b]​[1,5]​benzodiazepine, LY-170053
MDL NumberMFCD00866702
Beilstein Registry Number7655141
Reaxys-RN7655141
CAS Number132539-06-1
Merck Number6822
PubChem Substance ID160871343
Chemical Name Translation奥氮平
LabNetwork Molecule IDLN00189132
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分类

  • {SNA} Agonists, Antagonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Diversification Ready Pharma-Developed Compounds, Dopaminargics - Antagonists, Dopaminergics, Eli Lilly, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters, O, Serotonergics, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 蛋白质及衍生物
  • {SNA} Agonists, Antagonists, Approved Therapeutics/Drug Candidates, Biochemicals and Reagents, Cell Biol

相关文献及参考

  • [2]. Olanzapine for Injection, powder, for solution for intramuscular use.
  • [3]. Vucicevic L, et al. Autophagy inhibition uncovers the neurotoxic action of the antipsychotic drug olanzapine. Autophagy. 2014;10(12):2362-78.
  • [4]. Karpel-Massler G, et al. Olanzapine inhibits proliferation, migration and anchorage-independent growth in human glioblastoma cell lines and enhances temozolomide's antiproliferative effect. J Neurooncol. 2015 Mar;122(1):21-33.
  • [5]. Coccurello R, et al. Chronic administration of olanzapine induces metabolic and food intake alterations: a mousemodel of the atypical antipsychotic-associated adverse effects. Psychopharmacology (Berl). 2006 Jul;186(4):561-71.
  • [1]. APPROVED AGREED-UPON LABELING.
  • [1]. APPROVED AGREED-UPON LABELING.
  • [2]. Olanzapine for Injection, powder, for solution for intramuscular use.
  • [3]. Vucicevic L, et al. Autophagy inhibition uncovers the neurotoxic action of the antipsychoti

安全信息

GHS Symbol
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P310+P330
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P332+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H413 Maycauselonglastingharmfuleffectstoaquaticlife 可能对水生生物造成长期持续有害影响。
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H301 Toxic if swallowed 吞食有毒
WGK Germany3
Signal word Danger
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
Hazard Codes 6.1
Risk Statements
  • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
RTECSXJ9007750
UN Number 2811
Storage condition 0-10 0-10°C
Packing GroupIII
Hazard Class6.1

系列性分类


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