2H-1,4-Benzodiazepin-2-one,1,3-dihydro-7-chloro-5-(2-chlorophenyl)-1-(2-((4-methylphenyl)sulfonyl)ethyl)-

CAS 86273-92-9 MFCD00866974

化学结构图

86273-92-9
SMILES: CC1C=CC(=CC=1)S(=O)(=O)CCN1C2C=CC(Cl)=CC=2C(=NCC1=O)C1=CC=CC=C1Cl

化学属性

Mol. FormulaC24H20Cl2N2O3S
Mol. Weight487.42

别名和识别编码

Chemical Name2H-1,4-Benzodiazepin-2-one,1,3-dihydro-7-chloro-5-(2-chlorophenyl)-1-(2-((4-methylphenyl)sulfonyl)ethyl)-
Synonym Inn Tolufazepam 1-(4'-Methylphenylsulfonyl)ethyl-5-(2-chlorophenyl)-7-chloro-2H-1,4-benzodiazepin-2-one
CAS Number86273-92-9
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安全信息

RTECSDF2367730 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1350 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
   Behavioral - changes in motor activity (specific assay)
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 293,57,1988

系列性分类

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