(S)-(+)-Etodolac

CAS 87249-11-4 MFCD00870723

化学结构图

87249-11-4
SMILES: CC[C@@]1(CC(O)=O)OCCC2C3C=CC=C(CC)C=3NC1=2

化学属性

Mol. FormulaC17H21NO3
Mol. Weight287.39

别名和识别编码

Chemical Name(S)-(+)-Etodolac
CAS Number87249-11-4
Synonym (+)-Etodolic acid (+)-(S)-Etodolac (+)-Etodolic Acid RAK 592 (+)-1,8-Diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid RAK-592 S-Etodolac (S)-(+)-Etodolic Acid (+)-Etodolac (1S)-1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic Acid
Beilstein Registry Number5761988
Chemical Name Translation
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信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • Chiral Reagents
  • Heterocycles
  • Indole Derivatives
  • Pharmaceuticals
  • Intermediates & Fine Chemicals,

产品应用

  • The S-enantiomer of Etodolac (E933090). Anti-inflammatory; analgesic.

相关文献及参考

  • Boxenbaum, H., et al.: J. Pharmacokin. Biopharm., 10, 201 (1982),

安全信息

RTECSUQ0360015 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 420 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 40,737,1990

系列性分类

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