Pramipexole Dihydrochloride 普拉克索二盐酸盐

CAS 104632-25-9 MFCD00876894

化学结构图

104632-25-9
SMILES: CCCN[C@H]1CC2SC(N)=NC=2CC1

化学属性

Mol. FormulaC10H19Cl2N3S
Mol. Weight284

别名和识别编码

Chemical NamePramipexole Dihydrochloride
Synonym (S)-2-amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydrochloride PPX dihydrochloride Pramipexole dihydrochloride
MDL NumberMFCD00876894
Chemical Name Translation普拉克索二盐酸盐
CAS Number104632-25-9
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分类

  • {SNA} Agonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Boehringer Ingelheim, Dopaminergics, Dopaminergics - Agonists, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters, PI-PZ, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 蛋白质及衍生物
  • {SNA} Agonists, Approved Therapeutics/Drug Candidates, Biochemicals and Reagents, Boehringer Ingelheim, Cell Biology, Cell Signaling and Neuroscience, Dopaminergics,

相关文献及参考

  • [2]. Takashi Okura, et al. Blood-brain barrier transport of pramipexole, a dopamine D2 agonist. Life Sci. 2007 Apr 3;80(17):1564-71.
  • [3]. Ginetta Collo, et al. Ropinirole and Pramipexole Promote Structural Plasticity in Human iPSC-Derived Dopaminergic Neurons via BDNF and mTOR Signaling. Neural Plast. 2018; 2018: 4196961.
  • [4]. P M Carvey, et al. Attenuation of levodopa-induced toxicity in mesencephalic cultures by pramipexole. J Neural Transm (Vienna). 1997;104(2-3):209-28.
  • [5]. Syed Suhail Andrabi, et al. Pramipexole prevents ischemic cell death via mitochondrial pathways in ischemic stroke. Dis Model Mech. 2019 Aug 1; 12(8): dmm033860.
  • [1]. Kvernmo, T., et al. A review of the receptor-binding and pharmacokinetic properties of dopamine agonists. Clin Ther, 2006. 28(8): p. 1065-78.
  • [1]. Kvernmo, T., et al. A review of the receptor-binding and pharmacokinetic properties of dopamine agonists. Clin Ther, 2006. 28(8): p. 1065-78.
  • {MCE

安全信息

WGK Germany3

系列性分类


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