Taurohyodeoxycholic Acid Sodium Salt 牛磺酸脱氧胆酸钠盐

CAS 2958-04-5 MFCD00907891

化学结构图

2958-04-5
SMILES: C[C@@H](CCC(=O)NCCS(O)(=O)=O)[C@@H]1CC[C@@H]2[C@H]3C[C@@H](O)[C@H]4C[C@@H](O)CC[C@@]4(C)[C@@H]3CC[C@]21C |&1:1,13,16,17,19,21,23,27,29,32|

化学属性

Mol. FormulaC₂₆H₄₅NO₆S • xNa
Mol. Weight

别名和识别编码

Chemical NameTaurohyodeoxycholic Acid Sodium Salt
CAS Number2958-04-5
Synonym 2-[[(3?,5?,6?)-3,6-Dihydroxy-24-oxocholan-24-yl]amino]ethanesulfonic Acid N-(3?,6?-Dihydroxy-5?-cholan-24-oyl)taurine Taurine Hyodeoxycholate Taurohyodeoxycholic Acid Sodium Salt
Chemical Name Translation牛磺酸脱氧胆酸钠盐
InChIKeyHMXPOCDLAFAFNT-BHYUGXBJSA-N
MDL Number
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分类

  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Steroids

产品应用

  • A bile acid which stimulates the flow of bile salts, for potential treatment of Irritable Bile Syndrome.

相关文献及参考

  • [2]. Carubbi F, et, al. Comparative cytotoxic and cytoprotective effects of taurohyodeoxycholic acid (THDCA) and tauroursodeoxycholic acid (TUDCA) in HepG2 cell line. Biochim Biophys Acta. 2002 Jan 30;1580(1):31-9.
  • Gnewuch, C., et al.: World J. Gastroenterol., 15, 3134 (2009),
  • Lim, S., et al.: Int. J. Cancer, 126, 1582 (2010),
  • Yu, B., et al.: J. Nat. Prod., 72, 24 (2009),
  • [1]. Roda A, et, al. Taurohyodeoxycholic acid protects against taurochenodeoxycholic acid-induced cholestasis in the rat. Hepatology. 1998 Feb;27(2):520-5.
  • [1]. Roda A, et, al. Taurohyodeoxycholic acid protects against taurochenodeoxycholic acid-induced cholestasis in the rat. Hepatology. 1998 Feb;27(2):520-5.
  • [2]. Carubbi F, et, al. Comparative cytotoxic and cytoprotective effects of taurohyodeoxycholic acid (THDCA) and tauroursodeoxycholic acid (TUDCA) in HepG2 cell line. Biochim Biophys Acta. 2002 Jan 30;1580(1):31-9.

安全信息

Storage condition 4

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Endogenous Metabolite  (内源性代谢物)

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