2-Pyrrolidinone,1-(2-hydroxy-3-(4-phenyl-1-piperazinyl)propyl)-
CAS 148274-76-4 MFCD00915343
化学结构图
SMILES: OC(CN1CCN(CC1)C1C=CC=CC=1)CN1CCCC1=O
化学属性
| Mol. Formula | C17H25N3O2 |
|---|---|
| Mol. Weight | 303.45 |
别名和识别编码
| Chemical Name | 2-Pyrrolidinone,1-(2-hydroxy-3-(4-phenyl-1-piperazinyl)propyl)- |
|---|---|
| Synonym | 1-(2-Hydroxy-3-(4-phenyl-1-piperazinyl)propyl)-2-pyrrolidinone MG-1 N-(beta-Hydroxy-gamma-(N-phenylpiperazine)propyl)-2-pyrrolidinone |
| Beilstein Registry Number | 4328597 |
| CAS Number | 148274-76-4 |
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相关文献及参考
- [1]. Nowaczyk A, et al. QSAR studies on a number of pyrrolidin-2-one antiarrhythmic arylpiperazinyls. Med Chem Res. 2012 Mar;21(3):373-381.
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 160 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PJPPAA Polish Journal of Pharmacology and Pharmacy. (ARS Polona, POB 1001, 00-068 Warsaw 1, Poland) V.25- 1973- Volume(issue)/page/year: 44,561,1992
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 250 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PJPPAA Polish Journal of Pharmacology and Pharmacy. (ARS Polona, POB 1001, 00-068 Warsaw 1, Poland) V.25- 1973- Volume(issue)/page/year: 44,561,1992
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 290 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PJPPAA Polish Journal of Pharmacology and Pharmacy. (ARS Polona, POB 1001, 00-068 Warsaw 1, Poland) V.25- 1973- Volume(issue)/page/year: 44,561,1992
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