Dimethylenastron 2,3,4,6,7,8-六氢-4-(3-羟基苯基)-7,7-二甲基-2-硫代-5(1H)-喹唑啉酮

CAS 863774-58-7 MFCD09264157

化学结构图

863774-58-7
SMILES: CC1(C)CC2NC(=S)NC(C=2C(=O)C1)C1C=C(O)C=CC=1

化学属性

Mol. FormulaC16H18N2O2S
Mol. Weight302.396

别名和识别编码

Chemical NameDimethylenastron
Chemical Name Translation2,3,4,6,7,8-六氢-4-(3-羟基苯基)-7,7-二甲基-2-硫代-5(1H)-喹唑啉酮
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相关文献及参考

  • [2]. Sun XD, et al. Dimethylenastron suppresses human pancreatic cancer cell migration and invasion in vitro via allosteric inhibition of mitotic kinesin Eg5. Acta Pharmacol Sin. 2011 Dec;32(12):1543-8.
  • [3]. Lüke J, et al. The effect of adjuvant dimethylenastron, a mitotic Kinesin Eg5 inhibitor, in experimental glaucoma filtration surgery. Curr Eye Res. 2010 Dec;35(12):1090-8.
  • [1]. Gartner M, et al. Development and biological evaluation of potent and specific inhibitors of mitotic Kinesin Eg5. Chembiochem. 2005 Jul;6(7):1173-7.
  • [1]. Gartner M, et al. Development and biological evaluation of potent and specific inhibitors of mitotic Kinesin Eg5. Chembiochem. 2005 Jul;6(7):1173-7.
  • [2]. Sun XD, et al. Dimethylenastron suppresses human pancreatic cancer cell migration and invasion in vitro via allosteric inhibition of mitotic kinesin Eg5. Acta Pharmacol Sin. 2011 Dec;32(12):1543-8.
  • [3]. Lüke J, et al. The effect of adjuvant dimethylenastro

系列性分类

  1. Medical Research Areas
  2. Cytosketetal Signaling
  3. Kinesin  (驱动蛋白)

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