3-(1-BENZYL-2-ETHYL-3-CARBOXAMIDOMETHYLINDOL-5-YL)-PROPANEPHOSPHONIC ACID
CAS 164083-84-5 MFCD00943218
化学结构图
SMILES:
化学属性
| Mol. Formula | C22H27N2O5P |
|---|---|
| Mol. Weight | 430.43 |
别名和识别编码
| Chemical Name | LY311727 |
|---|---|
| MDL Number | MFCD00943218 |
| CAS Number | 164083-84-5 |
| Synonym | |
| PubChem Substance ID | 329817644 |
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分类
- {SNA} Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Eli Lilly, L, Lipids in Cell Signaling, Phospholipase Inhibitors, Phospholipid Metabolism, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Eli Lilly, L, Lipids in Cell Signaling, Phospholipase Inhibitors, Phospholipid Metabolism
相关文献及参考
- Schevitz, R.W., et al., Structure-based design of the first potent and selective inhibitor of human non-pancreatic secretory phospholipase A2. Nat. Struct. Biol. 2 , 458-465, (1995) 摘要
- Fleisch, J.H, et al., Recombinant human secretory phospholipase A2 released thromboxane from guinea pig bronchoalveolar lavage cells: in vitro and ex vivo evaluation of a novel secretory phospholipase A2 inhibitor. J. Pharmacol. Exp. Ther. 278 , 252-257, (1996)
- Bidgood, M.J., et al., Type IIA secretory phospholipase A2 up-regulates cyclooxygenase-2 and amplifies cytokine-mediated prostaglandin production in human rheumatoid synoviocytes. J. Immunol. 165 , 2790-2797, (2000) 摘要
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