PD 150606
CAS 179528-45-1 MFCD00949076
化学结构图
SMILES: OC(=O)/C(/S)=C/C1C=CC(I)=CC=1
化学属性
| Mol. Formula | C9H7IO2S |
|---|---|
| Mol. Weight | 306.12 |
别名和识别编码
| Chemical Name | PD 150606 |
|---|---|
| Synonym | (2Z)-3-(4-iodophenyl)-2-mercapto-2-Propenoic acid 3-(4-iodophenyl)-2-mercapto-(Z)-2-propenoic acid PD 150606 |
| MDL Number | MFCD00949076 |
| Chemical Name Translation | |
| PubChem Substance ID | 329798817 |
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信息真实价格透明
资金保障
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分类
- {SNA} Bioactive Small Molecule Alphabetical Index, Calpain and Proteasome Inhibitors, Endoplasmic Reticulum Stress, P-PH, Proteasome Inhibitors, 一氧化氮和细胞应激, 生物活性小分子, 细胞信号转导和神经科学, 细胞内蛋白降解, 细胞生物学
- {SNA} Bioactive Small Molecules, Calpain and Proteasome Inhibitors, Cell Biology, Cell Signaling and Neuroscience, Endoplasmic Reticulum Stress, Intracellular Protein Degradation, Nitric Oxide and Cell Stress, P, Proteasome Inhibitors
相关文献及参考
- [2]. 2. Squier MK , et al. Calpain and calpastatin regulate neutrophil apoptosis. J Cell Physiol. 1999 Mar;178(3):311-9.
- [1]. 1. Wang KK et al. An alpha-mercaptoacrylic acid derivative is a selective nonpeptide cell-permeable calpain inhibitor and is neuroprotective. Proc Natl Acad Sci U S A. 1996 Jun 25;93(13):6687-92.
- [1]. 1. Wang KK et al. An alpha-mercaptoacrylic acid derivative is a selective nonpeptide cell-permeable calpain inhibitor and is neuroprotective. Proc Natl Acad Sci U S A. 1996 Jun 25;93(13):6687-92.
- [2]. 2. Squier MK , et al. Calpain and calpastatin regulate neutrophil apoptosis. J Cell Physiol. 1999 Mar;178(3):311-9.
安全信息
GHS Symbol
- P301+P310
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H317 May cause an allergic skin reaction 可能导致皮肤过敏
- H318 Causes serious eye damage 严重伤害眼睛
- H301 Toxic if swallowed 吞食有毒
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
- R25 Toxic if swallowed 吞咽有毒
- R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
- R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
- R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
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