6-((4-bromothiophen-2-yl)methoxy)-3,9-dihydro-2H-purin-2-imine 罗米鲁曲

CAS 192441-08-0 MFCD N/A

化学结构图

192441-08-0
SMILES:

化学属性

Mol. Weight326.17
Mol. FormulaC10H8BrN5OS

别名和识别编码

CAS Number192441-08-0
Chemical Name6-((4-bromothiophen-2-yl)methoxy)-3,9-dihydro-2H-purin-2-imine
Synonym 6-[(4-Bromo-2-thienyl)methoxy]-9H-purin-2-amine 6-[(4-Bromo-2-thienyl)methoxy]
Chemical Name Translation罗米鲁曲
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分类

  • Amines
  • Heterocycles
  • Inhibitors
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Sulfur & Selenium Compounds

产品应用

  • Lomeguatrib is an inhibitor of O6-methylguanine-DNA methyltransferase (MGMT). Lomeguatrib attenuates MGMT activity in vitro and in vivo. Lomeguatrib enhances the antitumor activity of temozolomide in

相关文献及参考

  • Reinhard, et al.: J. Med. Chem., 44, 4050 (2001),
  • Barvaux, et al.: Mol. Cancer Ther., 3, 1215 (2004),
  • Clemons, et al., Br. J. Cancer, 93, 1152 (2005),

系列性分类

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