2-Fluoro-4-(trifluoromethyl)pyridine 2-氟-4-三氟甲基吡啶

CAS 118078-66-3 MFCD09879262

化学结构图

118078-66-3
SMILES: FC1C=C(C=CN=1)C(F)(F)F

化学属性

Mol. FormulaC6H3F4N
Mol. Weight165.09
Density1.355 g/mL at 25 °C
Refractive index1.3990 to 1.4030
TSCANo
Boiling Point110°
Flash Point23°C(lit.)

别名和识别编码

Chemical Name2-Fluoro-4-(trifluoromethyl)pyridine
CAS Number118078-66-3
Alfabeta NameFLUOROTRIFLUOROMETHYLPYRIDINE 24()---
MDL NumberMFCD09879262
Synonym 2-氟-4-三氟甲基吡啶
Chemical Name Translation2-氟-4-三氟甲基吡啶
PubChem Substance ID253660504
LabNetwork Molecule IDLN00130014
Reaxys-RN9758497
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分类

  • {SA} Building Blocks, C5 to C6, C6 to C7, Chemical Synthesis, Fluorinated Building Blocks, Halogenated Heterocycles, Heterocyclic Building Blocks, Heterocyclic Fluorinated Building Blocks, Other Fluorinated Heterocycles, Pyridines
  • {SNA} Building Blocks, C6, Chemical Synthesis,

相关文献及参考

  • 1. Pasumansky, L.; et al., Synthesis of aminopyridines from 2-fluoropyridine and lithium amides Tetrahedron Lett. 45 , 6417-6420, (2004)
  • 2. Izawa, Y.; Stahl, S. S., Aerobic oxidative coupling of o-xylene: Discovery of 2-fluoropyridine as a ligand to support selective Pd-catalyzed C-H functionalization Adv. Synth. Catal. 352 , 3223-3229, (2010)

安全信息

Warnings IRRITANT
WGK Germany3
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P301 IF SWALLOWED: 如果吞下去
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P310
  • P305+P351+P338
  • P301+P310+P330
  • P302+P352+P332+P313+P362+P364
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P305+P351+P338+P337+P313
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P405 Store locked up. 上锁保管。
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P403+P235
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
Signal word Danger
Hazard statements
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H315 Causes skin irritation 会刺激皮肤
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H301 Toxic if swallowed 吞食有毒
  • H319 Causes serious eye irritation 严重刺激眼睛
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
Risk Statements
  • R10 Flammable 易燃
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R25 Toxic if swallowed 吞咽有毒
  • R22 Harmful if swallowed 吞咽有害
Hazard Codes T
Hazard Class3/6.1
UN Number 1992
Packing GroupIII

系列性分类


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