3-Fluoropyridine 3-氟吡啶

CAS 372-47-4 MFCD00006374


SMILES: Fc1cccnc1


Mol. FormulaC5H4FN
Mol. Weight97
Boiling Point106°C(lit.)
Refractive index1.4720 to 1.4750
Flash Point13°C(lit.)
Appearance 无色透明液体
Melting Point251-254°C (dec.)


Chemical Name3-Fluoropyridine
CAS Number372-47-4
MDL NumberMFCD00006374
Synonym 3-fluoropyridine 3-FLUOROPYRIDINE 3-fluoro-pyridine 3-FLUOROPYRIDINE 98% (GC) Pyridine, 3-fluoro- 3-Fluoroypyridine 3-Fluor-pyridin 3-Fluoropyridine 98% 3-氟吡啶 3-Fluorpyridin 3-Fluoropyridine,98% 3-氟吡啶; 间氟吡啶 3-氟吡啶,98% 间氟吡啶
EC Number206-755-4
Beilstein Registry Number20(3/4)2492
PubChem Substance ID87569987
Chemical Name Translation3-氟吡啶
LabNetwork Molecule IDLN00007125
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  • {SNA} Building Blocks, C5, Chemical Synthesis, Fluorinated Building Blocks, Heterocyclic Building Blocks, Heterocyclic Fluorinated Building Blocks, Other Fluorinated Heterocycles, Pyridines
  • {uni_hamburg} no charge; nitrogen heterocycle; aromatic; 6RingOnly; 6ring; 1fragment


  • Metallation with LDA appears to occur initially mainly at the 2-position, but after longer reaction times, the 4-lithio derivative is the major product: Tetrahedron, 39, 2009 (1983). For a more recent example of 4-lithiation, see: Heterocycles, 35, 151 (1994).
  • Short: II/14a
  • {
  • Short: II/19b
  • Short: II/14b


Signal word
GHS Symbol
WGK Germany3
Safety Statements
  • S33 Take precautionary measures against static discharges 对静电采取预防措施;
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S37 Wear suitable gloves 戴适当手套;
  • S7 Keep container tightly closed 保存在严格密闭容器中;
Risk Statements
  • R11 Highly flammable 非常易燃
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P332+P313
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338+P337+P313
  • P303+P361+P353
  • P233 Keep container tightly closed. ?保持容器密闭。
  • P241+P242+P243
  • P403+P235
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H319 Causes serious eye irritation 严重刺激眼睛
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Packing GroupII
UN Number UN 1993 3/PG 2 1993
Hazard Codes
Hazard Class3
Storage condition Flammables area


  • Acros Organics:3-氟吡啶 3-Fluoropyridine, 99%(372-47-4)
  • TCI Shanghai:3-氟吡啶 3-Fluoropyridine,>;98.0%(GC)(372-47-4)
  • Hazard Note:Flammable/Irritant
  • 用途一:用作医药、农药中间体
  • MSDS 信息:3-Fluoropyridine(372-47-4).msds
  • 3-氟吡啶价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 F0207 3-氟吡啶 3-Fluoropyridine 5G 722元 2014/06/02 F0207 3-氟吡啶 3-Fluoropyridine 25G 2380元 2010/06/21 188300010 3-氟吡啶 3-Fluoropyridine 99% 1 GR 188元
  • MOL 文件:372-47-4.mol
  • 下游产品:5-氟-2-吡啶羧酸 --> 3-氟-4-氯吡啶盐酸盐 --> 2-氯-3-氟异烟酸 --> 4-氨基-3-氟吡啶 --> 3-氟吡啶-2-羧酸 --> 3-氟-4-吡啶硼酸 --> 3-氟-2-碘吡啶-4-羧酸
  • Alfa Aesar:3-氟吡啶,98% 3-Fluoropyridine, 98%(372-47-4)
  • 图谱信息:3-氟吡啶(372-47-4)质谱(MS) 3-氟吡啶(372-47-4)红外图谱(IR1) 3-氟吡啶(372-47-4)核磁图( 1 HNMR)
  • Sigma Aldrich:372-47-4(sigmaaldrich)