Avanafil 阿伐那非

CAS 330784-47-9 MFCD30784479

化学结构图

330784-47-9
SMILES: COC1C=CC(CNC2N=C(N=CC=2C(=O)NCC2N=CC=CN=2)N2CCCC2CO)=CC=1Cl

化学属性

Mol. Weight484
Mol. FormulaC23H26ClN7O3

别名和识别编码

CAS Number330784-47-9
Chemical NameAvanafil
Synonym ########
Chemical Name Translation阿伐那非
MDL NumberN/A
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分类

  • Aromatics
  • Chiral Reagents
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • A phosphodiesterase

相关文献及参考

  • [2]. Wang R, et al. Selectivity of avanafil, a PDE5 inhibitor for the treatment of erectile dysfunction: implications for clinical safety and improved tolerability. J Sex Med. 2012 Aug;9(8):2122-9.
  • [3]. Mochida H, et al. Avanafil, a highly selective phosphodiesterase type 5 inhibitor for erectile dysfunction, shows good safety profiles for retinal function and hemodynamics in anesthetized dogs. J Urol. 2013 Aug;190(2):799-806.
  • Hatzimouratidis, K., et al.: Drugs, 68, 231 (2008),
  • [1]. Kotera J, et al. Avanafil, a potent and highly selective phosphodiesterase-5 inhibitor for erectile dysfunction. J Urol. 2012 Aug;188(2):668-74.
  • [1]. Kotera J, et al. Avanafil, a potent and highly selective phosphodiesterase-5 inhibitor for erectile dysfunction. J Urol. 2012 Aug;188(2):668-74.
  • [2]. Wang R, et al. Selectivity of avanafil, a PDE5 inhibitor for the treatment of erectile dysfunction: implications for clinical safety and improved tolerability. J

安全信息

GHS Symbol

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Phosphodiesterase (PDE)  (磷酸二酯酶)

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