Bis(2-Ethylhexyl) Phthalate 邻苯二甲酸二(2-乙基己)酯

CAS 117-81-7 MFCD00009493

化学结构图

117-81-7
SMILES: CCCCC(CC)COC(=O)c1ccccc1C(=O)OCC(CC)CCCC

化学属性

Mol. FormulaC24H38O4
Mol. Weight390.56
Boiling Point386°C at 760 mmHg
Density0.985
Refractive index1.4850 to 1.4880
Flash Point207°C
TSCAYes
Melting Point-50°C
Autoignition Point734 °F
Vapor Density>;16 (vs air)
Vapor Pressure1.2 mmHg ( 93 °C)
Solubility可忽略
Stability对湿度敏感

别名和识别编码

Chemical NameBis(2-Ethylhexyl) Phthalate
CAS Number117-81-7
Synonym 1,2-Benzenedicarboxylic Acid 1,2-bis(2-ethylhexyl) Ester 1,2-Benzenedicarboxylic acid, bis(ethylhexyl) ester 1,2-benzenedicarboxylicacid,bis(2-ethylhexyl)ester 2-ETHYLHEXYL PHTHALATE Bis(2-ethylhexyl) phthalate Bis(2-ethylhexyl)phthalate Corflex 400 DEHP DOF DOP Di 2 Ethylhexylphthalate Di(2-ethylhexyl)phthalate Di-2-Ethylhexylphthalate Diethylhexyl Phthalate Dioctyl Phthalate Ergoplas Etalon Etalon (plasticizer) Garbeflex DOP-D 40 Kodaflex DEHP Kodaflex DOP NCI-C52733 Phthalate, Diethylhexyl Phthalate, Dioctyl Phthalic acid bis(2-ethylhexyl ester) Sansocizer DOP Sicol 150 Truflex DOP bis(2 {uni_hamburg}
PubChem Substance ID8343
EC Number204-211-0
Beilstein Registry Number1890696
MDL NumberMFCD00009493
Reaxys-RN1890696
Merck Number2864
Chemical Name Translation邻苯二甲酸二(2-乙基己)酯
Wiswesser Line Notation4Y2&1OVR BVO1Y4&2
LabNetwork Molecule IDLN00199675
InChIInChI=1S/C24H38O4/c1-5-9-13-19(7-3)17-27-23(25)21-15-11-12-16-22(21)24(26)28-18-20(8-4)14-10-6-2/h11-12,15-16,19-20H,5-10,13-14,17-18H2,1-4H3
Canonical SMILESO=C(C1=CC=CC=C1C(OCC(CC)CCCC)=O)OCC(CC)CCCC
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分类

  • {SNA} Ion Sensor Materials, Plasticizer for ISE, 分析/色谱
  • {SNA} Building Blocks, C12 to C63, Carbonyl Compounds, Chemical Synthesis, Esters, Organic Building Blocks
  • {SNA} 2000/60/EC, A-B, Additional Standards, Analytical Standards, Aromatics, Chemical Class, Esters, European Community: ISO, DIN and DL 152, Food & Beverage Standards, Food Residuals, Food and Cosmetic Component Standards, Method and Regulation Specific, Oeko-Tex Standard 100, Phthalates, Plasticizer, Plasticizers, Plasticizers (phthalates),

产品应用

  • 气相色谱固定液(最高使用温度150℃溶剂为甲醇主、二氯甲烷)选择性保留和分离芳香族化合物、不饱和化合物以及各种含氧化物(醇、醛、酮及酯等)，增塑剂。

相关文献及参考

  • Heindel, J., et al.: Toxicol. Appl. Pharmacol., 115, 116
  • Short: III/38A
  • Short: IV/15A
  • Short: III/38B
  • Merck: 14,2864 Beilstein: 9,IV,3181
  • Merck: 14,2864

安全信息

Hazard statements
  • H316 Causes mild skin irritation 会轻微的刺激皮肤
  • H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
Hazard Codes 9 T
GHS Symbol
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P304+P340
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P308+P313
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
  • P314 Get medical advice/attention if you feel unwell. 获取医疗咨询/就医，如果你觉得不舒服
  • P332+P313
  • P337+P313
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
WGK Germany1
Signal word Danger
Personal Protective Equipment Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSTI0350000
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S53 Avoid exposure - obtain special instructions before use 避免接触，使用前获得特别指示说明；
Risk Statements
  • R60 May impair fertility 可能降低生殖能力
  • R61 May cause harm to the unborn child 可能对未出生的婴儿导致伤害
UN Number 3082
Packing GroupIII
Storage condition 2-8°C Store at room temperature 低温(＜10℃)及避光条件下存放。 密封保存。
Hazard Class9 
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 519 gm/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-217,1982

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 438 gm/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
REFERENCE :
   CALEDQ Cancer Letters (Shannon, Ireland).  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1975- Volume(issue)/page/year:
   38,15,1987

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 433 gm/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
   Reproductive - Tumorigenic effects - testicular tumors
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-217,1982

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 524 gm/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
REFERENCE :
   EVHPAZ EHP, Environmental Health Perspectives.  (U.S. Government Printing
   Office, Supt of Documents, Washington, DC 20402)  No.1-    1972-
   Volume(issue)/page/year: 65,271,1986

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OB

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1500 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - structural or functional change in trachea
   or bronchi
   Gastrointestinal - necrotic changes
REFERENCE :
   TPKVAL Tok

TYPE OF TEST            : LD50 - Lethal

TYPE OF TEST            : LD50 - Lethal dose

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 30 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National
   Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair
   Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015)
   Volume(issue)/page/year: 2,32,1975

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intratracheal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 30 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - structural or functional change in trachea
   or bronchi
   Blood - hemorrhage
REFERENCE :
   TPKVAL Toksikologiya Novykh Promyshle

TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : >31 mL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AMIHAB AMA Archives of Industrial Health.  (Chicago, IL)  V.11-21, 1955-60.
   For publisher information, see AEHLAU.  Volume(issue)/page/year: 13,259,1956

TYPE OF TEST            : LD50 -

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Leukocyte
DOSE/DURATION           : 6 mg/L
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 65,1648,1976

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 50 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 211,77,1989

TYPE OF TEST            : Sex chromosome loss and nondisjunction
TEST SYSTEM             : Rodent - hamster Liver
DOSE/DURATION           : 50 mg/L
REFERENCE :
   PMRSDJ Progress in Mutation Research.  (Elsevier Science Pub. Co., Inc., 52
   Vanderbilt Ave., New York, NY 10017)  V.1-    1981- Volume(issue)/page/year:
   5,397,1985

TYPE OF TEST            : S

TYPE OF TEST            : Dominant lethal test
ROUTE OF EXPOSURE       : Subcutaneous
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 2970 mg/kg/10D (Intermittent)
REFERENCE :
   JTEHD6 Journal of Toxicology and Environmental Health.  (Hemisphere Pub.,
   1025 Vermont Ave., NW, Washington, DC 20005)  V.1-    1975/76-
   Volume(issue)/page/year: 16,71,1985

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 1541 mg/L
REFERENCE :
   PMRSDJ Progress in Mutation Research.  (Elsevier

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 500 umol/L
REFERENCE :
   PMRSDJ Progress in Mutation Research.  (Elsevier Science Pub. Co., Inc., 52
   Vanderbilt Ave., New York, NY 10017)  V.1-    1981- Volume

{hazard_co

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 50 mg/kg
SEX/DURATION            : female 7 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   EVHPAZ EHP, Environmental Health Perspectives.  (U.S. Government Printing
   Office, Supt of Documents, Washington, DC 20402)  No.1-    1972-
   Volume(issue)/page/year: 45,71,1982

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERV

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 9766 mg/kg
SEX/DURATION            : female 12 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
   Reproductive - Specific Developmental Abnormalities - cardiovascular
   (circulatory) system
   Reproductive - Specific Developmental Abnormalities - urogenital system
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 35,41,1987

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 5 gm/kg
SEX/DURATION            : female 5-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 61,51,1972

{haz

其他信息

  • 邻苯二甲酸二(2-乙基己)酯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 30060428 邻苯二甲酸二（2-乙基己基）酯;邻苯二甲酸二异辛酯; 邻酞酸二异辛酯 500ml 29元 2011/08/23 40014960 邻苯二甲酸二（2-乙基己基）酯;邻苯二甲酸二异辛酯; 邻酞酸二异辛酯 25ml 70元 2011/04/16 P0297 邻苯二甲酸双(α-乙基己基)酯 Bis(2-ethylhexyl) Phthalate 25G 167元
  • 海关编码:29173400
  • 毒性分级:中毒
  • 微有气味，能溶于专款专用脂肪烃和芳香烃，微溶于甘油，不溶于水
  • Acros Organics:双-2-乙基己基邻苯二甲酸酯(DEHP) Dioctyl phthalate, 99%(117-81-7)
  • 蒸气密度:>;16 (vs air)
  • 灭火剂:水, 二氧化碳, 干粉, 砂土
  • 刺激数据:皮肤- 兔 500 毫克/24小时 轻度; 眼睛- 兔 500 毫克 轻度
  • 图谱信息:邻苯二甲酸二(2-乙基己)酯(117-81-7)红外图谱(IR1) 邻苯二甲酸二(2-乙基己)酯(117-81-7)核磁图( 13 CNMR) 邻苯二甲酸二(2-乙基己)酯(117-81-7)质谱(MS) 邻苯二甲酸二(2-乙基己)酯(117-81-7)红外图谱(IR2) 邻苯二甲酸二(2-乙基己)酯(117-81-7)核磁图( 1 HNMR)
  • 上游原料:硫酸 --> 碳酸钠 --> 对甲
  • {
  • MSDS 信息:邻苯二甲酸二(2-乙基己基)酯(117-81-7).msds
  • 用途六:气相色谱固定液(最高使用温度150℃溶剂为甲醇主、二氯甲烷)选择性保留和分离芳香族化合物、不饱和化合物以及各种含氧化物(醇、醛、酮及酯等)，增塑剂。
  • 外观性质:无色或淡黄色粘稠液体，微有气味。
  • 爆炸物危险特性:与空气混合可爆; 与氧化剂反应激烈
  • 用途二:用作耐寒增塑剂
  • 用途三:用作气相色谱固定剂、增塑剂
  • 方法一:增塑剂的用量很大，品种繁多。目前增塑剂生产技术的发展趋势，一方面是主增塑剂的连续化大生产，另一方面是特殊增塑剂的多品种、小批量的间歇生产。邻苯二甲酸酯类增塑剂的消费量约占增塑剂总量的80%，生产量很大，因而出现了以邻苯二甲酸二辛酯为中心的连续化大生产。邻苯二甲酸酯在工业上都是用苯酐与相应的醇在硫酸、对甲苯磺酸等酸性催化剂存在下酯化制得的，酸性催化剂的用量一般以苯酐计为0.2-0.5%。由苯酐与2-乙基己醇（异辛醇）在硫酸或钛酸酯、氧化亚锡、铝酸盐等非酸性催化剂催化下进行酯化反应，酯化液经中和、水洗、脱醇、脱色、压滤得成品。原料消耗定额：苯酐383kg/t、2-乙基己醇（95%）671kg/t、硫酸6kg/t、纯碱10kg/t。
  • 急性毒性:口服- 大鼠 LD50: 30000 毫克/ 公斤; 口服- 小鼠 LD50: 1500 毫克/ 公斤
  • 下游产品:邻苯二甲酸二癸酯 --> 酞酸二异癸酯 --> 过氧化环己酮
  • 用途一:可用作DOP的替代品，特别适用于增塑糊中，粘度稳定性好
  • 用途五:该品是最广泛使用的增塑剂，除了乙酸纤维素、聚乙酸乙烯外，与绝大多数工业上使用的合成树脂和橡胶均有良好的相容性。本品具有良好的综合性能，混合性能好，增塑效率高，挥发性较低，低温柔软性较好，耐水抽出，电气性能高，耐热性和耐候性良好。该品作为一种主增塑剂，广泛应用于聚氯乙烯各种软质制品的加工，例如薄膜、薄板、人造革、电缆料和模塑品等。该品无毒，可用于与食物接触的包装材料，但由于易被脂肪抽出，故不宜用于脂肪性食品包装材料。还可用于硝基纤维素漆，使漆膜具有弹性的较高的抗张强度。在多种合成橡胶中，该品亦有良好的软化作用。另外，DOP还用作缩合剂、减磨剂、有机溶剂、气相色谱固定液。
  • 类别:农药
  • 用途四:用作塑料的主增塑剂，广泛用于聚氯乙烯制品中
  • 凝固点:

系列性分类

  1. Analytical & Chromatography 分析化学与色谱
  2. Ion Sensor Materials
  3. Plasticizer for ISE - Ion Sensor Materials
  1. Analytical & Chromatography 分析化学与色谱
  2. Ion Sensor Materials
  3. Plasticizer for ISE - Ion Sensor Materials
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Alphabetic - Analytical Standards
  4. D - Alphabetic
  5. DID - DIN - D
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Carbonyl Compounds 羰基化合物
  5. Esters - Carbonyl Compounds
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Carbonyl Compounds 羰基化合物
  5. Esters - Carbonyl Compounds
  6. C12 to C63 - Esters
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Carbonyl Compounds 羰基化合物
  5. Esters - Carbonyl Compounds
  6. C12 to C63 - Esters
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Method Specific - Analytical Standards
  4. European Community: ISO, DIN and DL 152 - Method Specific
  5. 2000/60/EC - European Community: ISO, DIN and DL 152
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Alphabetic - Analytical Standards
  4. B - Alphabetic
  5. BI - BZ - B
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Chromatography - Analytical Standards
  4. Environmental Standards - Chromatography
  5. Volatiles/ Semivolatiles - Environmental Standards
  6. Alpha Sort - Volatiles/ Semivolatiles
  7. D - Alpha Sort
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Chromatography - Analytical Standards
  4. Cosmetic Standards - Chromatography
  5. Allergens - Cosmetic Standards
  6. Phthalates - Allergens
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Certified Reference Materials (CRMs) - Analytical Standards
  4. Organic CRMs TraceCERT - Certified Reference Materials (CRMs)
  5. CRM for chromatography - Organic CRMs TraceCERT
  6. Organic CRMs Alphabetical - CRM for chromatography
  1. Analytical & Chromatography 分析化学与色谱
  2. Environmental Endocrine Disruptors
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Carbonyl Compounds 羰基化合物
  5. Esters
  6. C10 to C11
  1. Materials Science 材料科学
  2. Plasticizer
  1. Medical Research Areas
  2. Metabolism
  3. Endogenous Metabolite  (内源性代谢物)