Benzidine Dihydrochloride (1,1-联苯)-4,4-二胺二盐酸盐

CAS 531-85-1 MFCD00040389

化学结构图

531-85-1
SMILES:

化学属性

Mol. FormulaC12H12N2· 2HCl
Mol. Weight257.16
Melting Point>=300 °C
Solubility0.1-0.5 G/100 ML AT 23.5 ºC
Appearance 白色片状结晶，熔点300℃，溶于水和乙醇，有毒，最小致死量(狗，经口)200mg/kg,有致癌可能性。
Stability对光敏感

别名和识别编码

Chemical NameBenzidine Dihydrochloride
MDL NumberMFCD00040389
CAS Number531-85-1
Synonym 4,4'-Diaminobiphenyl dihydrochloride BENZIDINE DIHYDROCHLORIDE benz [1,1'-biphenyl]-4,4'-diamine dihydrochloride BENZIDINE ISOPAC DIHYDROCHLORIDE p,p′-Diaminodiphenyl hydrochloride(1,1'-Biphenyl)-4,4'-diamine dihydrochloride 盐酸联苯胺 (1,1'-Biphenyl)-4,4'-diamine,dihydrochlorid (1,1'-Biphenyl)-4,4'-diamine, dihydrochloride 联苯胺盐酸盐,二盐酸联苯胺,联苯胺二盐酸盐, 4,4′-二氨基联苯盐酸盐,(1,1'-联苯)-4,4'-二胺二盐酸盐,盐酸-4,4'-二氨基联苯,联苯胺盐酸 BENZIDINE HYDROCHLORIDE (1,1'-联苯)-4,4'-二胺二盐酸盐 联苯胺 二盐酸盐 联苯胺盐酸 dihidroclorurodebenzidina 4,4'-Diaminobiphenyl dihydrochloride; [1,1'-Biphenyl]-4,4'-diamine dihydrochloride 联苯胺盐酸盐 {Chemicalbook}
PubChem Substance ID24891713
EC Number208-519-6
Beilstein Registry Number3914846
Chemical Name Translation(1,1-联苯)-4,4-二胺二盐酸盐
Wiswesser Line NotationZR DR DZ &GH 2
LabNetwork Molecule IDLN00193401
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} B, Hematology and Histology, Stains & Dyes, A to Z, Stains and Dyes, 细胞生物学
  • {SNA} B, Cell Biology, Hematology and Histology, Stains & Dyes, A to Z, Stains and Dyes
  • {SNA} B, Hematology and Histology, Stains & Dyes, A to Z, Stains and Dyes
  • {SNA} B, Stains & Dyes, A to Z,

产品应用

  • 定量测定硫酸盐和多种金属试剂，测定血液，检验氰化物，萃取稀有金属元素钍和铀。高纯级在生物学实验中用于诱发试验动物的乳腺癌。

相关文献及参考

  • Beilstein: 13,IV,365

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H350 May cause cancer 可能致癌
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
  • H302 Harmful if swallowed 吞食有害
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
RTECSDD0600000
Precautionary statements
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P308+P313
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P201 Obtain special instructions before use. 使用前获取专门指示。
Signal word Danger
Hazard Codes T,N T;N
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S53 Avoid exposure - obtain special instructions before use 避免接触，使用前获得特别指示说明；
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
Risk Statements
  • R45 May cause cancer 可能致癌
  • R22 Harmful if swallowed 吞咽有害
  • R50/53
UN Number 2811 UN 2811 6.1/PG 2
Storage condition 密封避光保存。
Warnings 危化品目录(2015) 危险化学品 
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1600 mg/kg/84W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
   Endocrine - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/

{haz

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1680 mg/kg/40W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
REFERENCE :
   TOPADD Toxicologic Pathology.  (c/o Dr. F.A. de la Iglesia, Warner-Lambert
   Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 
     1978-  Volume(issue)/page/year: 9,1,1981

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 62 mg/kg/4W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Endocrine - tumors
   Skin and Appendages - tumors
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 2,747,1981

TYPE OF

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 13440 mg/kg/1Y-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   4,69,1984

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 3 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 216,101,1989

TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 20 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 94,449,1982

TYPE OF TEST            : Sister chromatid exchange
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - hamster
DOSE/DURATION           : 12500 ug/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 113,33,1983

TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 400 mg/kg/48H (Continuous)
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 234,187,1990

TYPE OF TEST            : DNA damage
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 250 mg/kg
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   38,1589,1978

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 100 nmol/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Ams

其他信息

  • 储运特性:库房通风低温干燥; 与食品原料分开储运
  • 用途一:定量测定硫酸盐和多种金属试剂，测定血液，检验氰化物，萃取稀有金属元素钍和铀。高纯级在生物学实验中用于诱发试验动物的乳腺癌。
  • 毒性分级:高毒
  • Sigma Aldrich:531-85-1(sigmaaldrich)
  • 溶于水,稍溶于乙醇。有毒，最小致死量(狗，经口)200mg/kg。有致癌可能性。
  • MSDS 信息:4,4'-Diaminobiphenyl dihydrochloride(531-85-1).msds
  • 可燃性危险特性:可燃; 受热放出有毒氯化氢和氧化氮气体
  • 下游产品:联苯胺 --> 苯乙双胍
  • 灭火剂:水、二氧化碳、砂土、泡沫
  • MOL 文件:531-85-1.mol
  • 盐酸联苯胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80015314 联苯胺盐酸盐;二盐酸联苯胺;联苯胺二盐酸盐 25g 51.5元
  • 急性毒性:参考值: (联苯胺) 口服-大鼠 LD50: 309 毫克/公斤; 口服-小鼠 LD50; 214 毫克/公斤
  • 类别:有毒物品

系列性分类

  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Reagents
  3. Analytical Reagents for General Use - Analytical Reagents
  4. Puriss p.a. - Analytical Reagents for General Use
  1. Life Science 生命科学
  2. Hematology and Histology 血液学和组织学
  3. Stains and Dyes - Hematology and Histology
  4. Stains & Dyes, A to Z - Stains and Dyes
  5. B - Stains & Dyes, A to Z
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Reagents
  3. Analytical Reagents for General Use - Analytical Reagents
  4. Puriss p.a. - Analytical Reagents for General Use
  5. A-B, Puriss p.a. - Puriss p.a.

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