2-(2,2,2-Trifluoroacetyl)-1,2,3,4-Tetrahydroisoquinoline-7-Sulfonyl Chloride 1,2,3,4-四氢-2-(三氟乙酰基)异喹啉-7-磺酰氯

CAS 74291-57-9 MFCD01075651

化学结构图

74291-57-9
SMILES: O=C(N1CC2C=C(C=CC=2CC1)S(=O)(=O)Cl)C(F)(F)F

化学属性

Mol. FormulaC11H9ClF3NO3S
Mol. Weight328
Melting Point102-104°
TSCANo

别名和识别编码

Chemical Name2-(2,2,2-Trifluoroacetyl)-1,2,3,4-Tetrahydroisoquinoline-7-Sulfonyl Chloride
CAS Number74291-57-9
Synonym 1,2,3,4-Tetrahydro-2-(2,2,2-trifluoroacetyl)- 2-(Trifluoroacetyl)-1,2,3,4-tetrahydro-7-isoquinolinesulfonyl chloride
MDL NumberMFCD01075651
EC Number000-000-0
Beilstein Registry Number5603124
PubChem Substance ID329778355
Chemical Name Translation1,2,3,4-四氢-2-(三氟乙酰基)异喹啉-7-磺酰氯
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分类

  • Sulfur & Selenium Compounds
  • Heterocycles
  • {SNA} Building Blocks, Chemical Synthesis, Fluorinated Building Blocks, Halogenated Heterocycles, Heterocyclic Building Blocks, Heterocyclic Fluorinated Building Blocks, Other Fluorinated Heterocycles, Quinolines
  • Inhibitors
  • Aromatics

产品应用

  • An intermediate for the preparation of 5-heteroaryl thiazoles and their use as phosphoinositide 3-kinase (PI3K) inhibitors

相关文献及参考

  • Lowe, S., et al.: Carcinogenesis, 21, 485 (2000),

安全信息

Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S20 When using do not eat or drink 使用时,不得进食,饮水;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Packing GroupII
UN Number UN3261
Risk Statements
  • R34 Causes burns 会导致灼伤
Storage condition Moisture Sensitive
WGK Germany3

系列性分类


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