Ramifenazone 1,2-二氢-1,5-二甲基-4-(异丙基氨基)-2-苯基-3H-吡唑-3-酮

CAS 3615-24-5 MFCD00800727

化学结构图

3615-24-5
SMILES: Cc1c(NC(C)C)c(=O)n(-c2ccccc2)n1C

化学属性

Mol. FormulaC14H19N3O
Mol. Weight245

别名和识别编码

Chemical NameRamifenazone
CAS Number3615-24-5
EC Number222-791-3
Synonym 1,2-Dihydro-1,5-dimethyl-4-[(1-methylethyl)amino]-2-phenyl-3H-pyrazol-3-one 4-Monoisopropylamino-1-phenyl-2,3-dimethyl-5-pyrazolone 雷米那酮 Ramiphenazone Isopyrin 4-Isopropylamino-1-phenyl-2,3-dimethyl-3-pyrazolin-5-one Isopropylaminophenazon Isopyrine 1,2-Dihydro-1,5-dimethyl-4-isopropylamino-2-phenyl-3H-pyrazol-3-one 4-Isopropylamino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one Isopropylaminoantipyrine 3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)amino-2-phenyl- isopyrin Isopirina RAMIFENAZONE 1,2-二氢-1,5-二甲基-4-(异丙基氨基)-2-苯基-3H-吡唑-3-酮 1-Phenyl-2,3-dimethyl-4-(isopropylamino)-2-pyrazolin-5-one 3H-Pyrazol-3-one, 异丙基氨基比林 Ramifenazone; 4-Isopropylamino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one 异比林 4-isopropylamino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one 4-(Isopropylamino)antipyrine ISOPYRIN=RAMIFENAZONE,S.DORT Isopropylaminophenazone 异丙氨基比林 1-Phenyl-2,3-dimethyl-4-isopropylaminopyrazolone 4-Isopropylaminoantipyrine
MDL NumberMFCD00800727
Chemical Name Translation1,2-二氢-1,5-二甲基-4-(异丙基氨基)-2-苯基-3H-吡唑-3-酮
Wiswesser Line NotationT5NNVJ A1 BR& DMY1&1 E1
Beilstein Registry Number0231936
LabNetwork Molecule IDLN01343040
PubChem Substance ID5037
InChIInChI=1S/C14H19N3O/c1-10(2)15-13-11(3)16(4)17(14(13)18)12-8-6-5-7-9-12/h5-10,15H,1-4H3
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安全信息

RTECSCD2975000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 820 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 10,665,1960

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 450 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - hamster
DOSE/DURATION           : 567 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 20,1024,1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 690 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 10,665,1960

TYPE OF

其他信息

  • MOL 文件:3615-24-5.mol
  • 用途一:用作消炎镇痛药

系列性分类

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