Carbomycin [INN] 卡波霉素

CAS 4564-87-8 MFCD N/A

化学结构图

4564-87-8
SMILES: CO[C@@H]1[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](OC(=O)CC(C)C)[C@H](C)O3)[C@H](N(C)C)[C@H]2O)[C@H](CC=O)C[C@H](C)C(=O)/C=C/[C@@H]2O[C@@H]2C[C@@H](C)OC(=O)C[C@H]1OC(C)=O

化学属性

Mol. Weight842.10
Mol. FormulaC42H67NO16

别名和识别编码

CAS Number4564-87-8
Chemical NameLeucomycin V,9-deoxy-12,13-epoxy-12,13-dihydro-9-oxo-, 3-acetate4B-(3-methylbutanoate), (12S,13S)-
Synonym M-4209 (12S,13S)-9-Deoxy-12,13-epoxy-12,13-dihydro-9-oxoleucomycin V 3-Acetate 4B-(3-Methylbutanoate) NSC 55924 Carbomycin Magnamycin Carbomycin A NSC 51001 Magnamycin A M 4209 Deltamycin A4
Chemical Name Translation卡波霉素
InChIKeyFQVHOULQCKDUCY-LSWLKRQKSA-N
信息真实价格透明    资金保障    专业采购外包团队在线服务   
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品牌质保精细包装    现货库存    一流品牌服务   

分类

  • Amines
  • Chiral Reagents
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Sixteen-membered-ring macrolite antibiotic complex similar to Leucomycin and Erythromycin, produced by Stroptomyces halstedii.

相关文献及参考

  • Shimauchi, Y., et al.: J. Antibiot., 31, 270 (1978),
  • Davis, B., et al.: J. Mol. Biol., 336, 343 (2004),

安全信息

RTECSOH4727000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ABANAE Antibiotics Annual.  (New York, NY)  1953-60.  For publisher
   information, see AMACCQ.  Volume(issue)/page/year: 2,336,1954/1955

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ANTCAO Antibiotics and Chemotherapy (Washington, DC).  (Washington, DC)
   V.1-12, 1951-62.  For publisher information, see CLMEA3.
   Volume(issue)/page/year: 3,117,1953

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 550 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ANTCAO Antibiotics and Chemotherapy (Washington, DC).  (Washington, DC)
   V.1-12, 1951-62.  For publisher information, see CLMEA3.
   Volume(issue)/page/year: 3,117,1953

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2950 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ANTCAO Antibiotics and Chemotherapy (Washington, DC).  (Washington, DC)
   V.1-12, 1951-62.  For publisher information, see CLMEA3.
   Volume(issue)/page/year: 3,117,1953

系列性分类

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