Ellagic acid 柔花酸

CAS 476-66-4 MFCD00006914

化学结构图

476-66-4
SMILES: O=c1oc2c(O)c(O)cc3c(=O)oc4c(O)c(O)cc1c4c23

化学属性

Mol. FormulaC14H6O8
Mol. Weight302
Melting Point300
Density1.667
Solubility<0.1 G/100 ML AT 21 ºC
Appearance powder
Stability对空气敏感,对光敏感
Boiling Point

别名和识别编码

Chemical NameEllagic acid
Synonym 2,3,7,8-Tetrahydroxy(1)benzopyrano(5,4,3-cde)(1)benzopyran-5,10-dione 4,3-cde][1]benzopyran-5,10-dione,2,3,7,8-tetrahydroxy-[1]-Benzopyrano[5 4,4',5,5',6,6'-HEXAHYDROXYDIPHENIC ACID 2,6,2',6'-DILACTONE 4,4',5,5',6,6'-HEXAHYDROXYDIPHENIC ACID DILACTONE 4,4',5,5',6,6'-Hexahydroxydiphenic acid 2,6,2',6'-dilactone 4,4′,5,5′,6,6′-Hexahydroxydiphenic acid 2,6,2′,6′-dilactone AKOS NCG1-0028 Acid, Benzoaric Acid, Ellagic Benzoaric Acid Benzoaric acid Elagostasine Ellagic Acid Lagistase alizarineyellow c.i.75270 lagistase 二缩双(三羟基苯甲酸) 倍原 土耳其鞣酸 棓原;逆没食子酸,二缩双(三羟基甲酸); 2,3,7,8-四羟基-[1]-苯并吡喃并[5,4,3-CDE][1]苯并吡喃-5,10-二酮 逆没食子酸 鞣花酸二水化合物 鞣花酸水合物
MDL NumberMFCD00006914
Beilstein Registry Number47549
CAS Number476-66-4
EC Number207-508-3
PubChem Substance ID5281855
Chemical Name Translation柔花酸
Merck Number3547
Reaxys-RN47549
LabNetwork Molecule IDLN00196863
InChIInChI=1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Additional Standards, Alphabetical, Analytical Standards, Arctostaphylos, Chromatography, E - H, Eucalyptus, Life Sciences Standards, Natural Compounds, Phyllanthus, Phytochemicals Standards, Potentilla, Punica, Standards by Plant Genus, Substance Classification, Syzygium, Tannins, Terminalia, Tilia, 分析/色谱
  • {SNA} Additional Standards, Alphabetical Index of Phytochemical Standards, Analytical Standards, Arctostaphylos, Chromatography, E - H,
  • {SNA} Antioxidant and Free Radical

产品应用

  • 常见于多酚植物。谷胱甘肽S-转移酶的抑制剂,常用于检测血浆中XIIa 因子;抗氧化剂;DNA双链的保护剂。

相关文献及参考

  • [2]. Rizk HA, et al. Prophylactic effects of ellagic acid and rosmarinic acid on doxorubicin-induced neurotoxicity in rats. J Biochem Mol Toxicol. 2017 Dec;31(12).
  • [3]. Ahire V, et al. Ellagic Acid Enhances Apoptotic Sensitivity of Breast Cancer Cells to γ-Radiation. Nutr Cancer. 2017 Aug-Sep;69(6):904-910.
  • Merck: 14,3547
  • Merck: 14,3547 Beilstein:19,261
  • [1]. Cozza G, et al. Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application. J Med Chem. 2006 Apr 20;49(8):2363-6.
  • [1]. Cozza G, et al. Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application. J Med Chem. 2006 Apr 20;49(8):2363-6.
  • [2]. Rizk HA, et al. Prophylactic effects of ellagic acid and rosmarinic acid on doxorubicin-induced neurotoxicity in rats. J Biochem Mol Toxicol. 2017 Dec;31(12).
  • [3]. Ahire V, et al. Ellagic Acid E

安全信息

GHS Symbol
RTECSDJ2620000
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P350
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P332+P313
  • P332+P317
  • P337+P313
  • P337+P317
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P362+P364
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
WGK Germany1
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes Xi
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Storage condition 充氩密封避光保存。 对光和空气敏感,充氩密封避光保存。
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 1208 mg/kg
SEX/DURATION            : female 16 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - abortion
   Reproductive - Specific Developmental Abnormalities - blood and lymphatic
   systems (including spleen and marrow)
REFERENCE :
   AMBPBZ Acta Pathologica et Microbiologica Scandinavica, Section A:
   Pathology.  (Copenhagen, Denmark) V.78-89, 1970-81.  For publisher
   information, see ACPADQ.  Volume(issue)/page/year: 79,487,1971

UN Number
Packing Group

其他信息

  • Alfa Aesar:鞣花酸二水合物,97% Ellagic acid hydrate, 97%, may cont. up to 12% water(476-66-4)
  • color:tan to gray
  • 对光和空气敏感。溶于碱类和吡啶,微溶于水和乙醇,几乎不溶于乙醚。。有刺激性。商品也有含2分子结晶水的。
  • 鞣花酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 E0375 鞣花酸二水合物 Ellagic Acid Dihydrate 5G 530元 2014/06/02 E0375 鞣花酸二水合物 Ellagic Acid Dihydrate 25G 1580元 2010/05/25 A15722 鞣花酸二水合物, 97% Ellagic acid hydrate, 97%, may cont. up to 12% water 25g 1512元
  • Acros Organics:鞣花酸水合物 Ellagic acid hydrate, 97%(476-66-4)
  • MSDS 信息:4,4',5,5',6,6'-Hexahydroxydiphenic acid 2,6,2',6'-dilactone(476-66-4).msds
  • MOL 文件:476-66-4.mol
  • 用途一:用于医药及化妆品,作抗氧剂,具有防癌及抑制病毒作用
  • 敏感性:Air & Light Sensitive
  • 图谱信息:鞣花酸(476-66-4)质谱(MS) 鞣花酸(476-66-4)红外图谱(IR2) 鞣花酸(476-66-4)红外图谱(IR1)
  • TCI Shanghai:鞣花酸 Ellagic Acid Dihydrate(476-66-4)
  • F:8-10-23
  • Sigma Aldrich:476-66-4(sigmaaldrich)

系列性分类


相关产品推荐