1-(2-Methoxyethyl)piperazine 1-(2-甲氧基乙基)哌嗪

CAS 13484-40-7 MFCD00191214

化学结构图

13484-40-7
SMILES: COCCN1CCNCC1

化学属性

Mol. FormulaC7H16N2O
Mol. Weight144.22
Refractive index1.4700 to 1.4740
Boiling Point193-194
Density0.97
Flash Point87°(189°F)
TSCANo
Stability对空气敏感,易吸收CO2

别名和识别编码

Chemical Name1-(2-Methoxyethyl)piperazine
CAS Number13484-40-7
Alfabeta NameMETHOXYETHYLPIPERAZINE 12()----
MDL NumberMFCD00191214
Synonym 1-(2-甲氧基乙基)哌嗪 4-(2-Methoxyethyl)piperazine N-(2-Methoxyethyl)piperazine Methyl 2-(1-Piperazinyl)ethyl Ether N-(2-Methoxyethyl)piperazine
PubChem Substance ID125307892
Beilstein Registry Number105098
Reaxys-RN105098
EC Number250-023-7
Chemical Name Translation1-(2-甲氧基乙基)哌嗪
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分类

  • {SNA} Building Blocks, C4 to C8, Chemical Synthesis, Heterocyclic Building Blocks, Piperazines
  • Building Blocks, C4 to C8, Chemical Synthesis, Heterocyclic Building Blocks, Piperazines

相关文献及参考

  • 1. Byrtus, H.; et al., Synthesis and anticonvulsant activity of new N-Mannich bases derived from 5-cyclopropyl-5-phenyl- and 5-cyclopropyl-5-(4-chlorophenyl)-imidazolidine-2,4-diones Bioorg. Med. Chem. 19 , 6149-6156, (2011)
  • 2. Jones, P.; et al., Discovery of a highly potent series of TLR7 agonists Bioorg. Med. Chem. Lett. 21 , 5939-5943, (2011)
  • 3. Mohamed, T.; et al., Development of 2-substituted-N-(naphth-1-ylmethyl) and N-benzhydrylpyrimidin-4-amines as dual cholinesterase and Aβ-aggregation inhibitors: Synthesis and biological evaluation Bioorg. Med. Chem. Lett. 21 , 5881-5887, (2011)
  • 4. Mohamed, T.; et al., Design, synthesis and structure-activity relationship (SAR) studies of 2,4-disubstituted pyrimidine derivatives: Dual activity as cholinesterase and Aβ-aggregation inhibitors Bioorg. Med. Chem. 19 , 2269-2281, (2011)
  • 5. Cano, C.; et al., DNA-Dependent Protein Kinase (DNA-PK) Inhibitors: Synthesis and Biological Activity of Quinolin-4-one and Pyridopyrimidin-4-one Surrogates for the Chromen-4-one Chemotype J. Med. Chem. 53 , 8498-8507, (2010)

安全信息

Warnings IRRITANT
GHS Symbol
WGK Germany3
Hazard Codes 8 C
Hazard statements
  • H227 Combustible liquid 可燃液体
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P314 Get medical advice/attention if you feel unwell. 获取医疗咨询/就医,如果你觉得不舒服
  • P332+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P370+P378
  • P403+P235
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Danger
UN Number 2735
Risk Statements
  • R34 Causes burns 会导致灼伤
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Safety Statements
  • S20 When using do not eat or drink 使用时,不得进食,饮水;
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
Packing GroupIII

系列性分类


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