2-(Furan-2-Yl)-7-(3-(4-Methoxyphenyl)Propyl)-7H-Pyrazolo[4,3-E][1,2,4]Triazolo[1,5-C]Pyrimidin-5-Amine 2-(呋喃-2-基)-7-(3-(4-甲氧基苯基)丙基)-7H-吡唑啉[4,3-e][1,2,4]三唑[1,5-c]嘧啶-5-胺

CAS 316173-57-6 MFCD08703126

化学结构图

316173-57-6
SMILES: COC1C=CC(CCCN2N=CC3=C2N=C(N)N2N=C(N=C23)C2=CC=CO2)=CC=1

化学属性

Mol. FormulaC20H19N7O2
Mol. Weight389.41

别名和识别编码

Chemical Name2-(Furan-2-Yl)-7-(3-(4-Methoxyphenyl)Propyl)-7H-Pyrazolo[4,3-E][1,2,4]Triazolo[1,5-C]Pyrimidin-5-Amine
Synonym 2-(2-Furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine; 5-amino-7-(3-(4-methoxyphenyl)propyl)-2-(2 furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine; 5-Amino-7-[3-(4-methoxy)phenylpropyl]-2-(2-furyl)-pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine SCH-442416
MDL NumberMFCD08703126
PubChem Substance ID329824564
Chemical Name Translation2-(呋喃-2-基)-7-(3-(4-甲氧基苯基)丙基)-7H-吡唑啉[4,3-e][1,2,4]三唑[1,5-c]嘧啶-5-胺
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分类

  • {SNA} Bioactive Small Molecule Alphabetical Index, S, 生物活性小分子, 细胞生物学
  • {SNA} Bioactive Small Molecules, Cell Biology, S

相关文献及参考

  • [2]. Moresco RM, et, al. In vivo imaging of adenosine A2A receptors in rat and primate brain using [11C]SCH442416. Eur J Nucl Med Mol Imaging. 2005 Apr;32(4):405-13.
  • [3]. Zheng J, et, al. Protective roles of adenosine A1, A2A, and A3 receptors in skeletal muscle ischemia and reperfusion injury. Am J Physiol Heart Circ Physiol. 2007 Dec;293(6):H3685-91.
  • [4]. Maimon N, et, al. Pre-exposure to adenosine, acting via A(2A) receptors on endothelial cells, alters the protein kinase A dependence of adenosine-induced dilation in skeletal muscle resistance arterioles. J Physiol. 2014 Jun 15;592(12):2575-90.
  • [5]. Yu J, et, al. A 2A R Antagonists Upregulate Expression of GS and GLAST in Rat Hypoxia Model. Biomed Res Int. 2020 Oct 26;2020:2054293.
  • [1]. Todde S, et, al. Design, radiosynthesis, and biodistribution of a new potent and selective ligand for in vivo imaging of the adenosine A(2A) receptor system using positron emission tomography. J Med Chem.

安全信息

WGK Germany3

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. S - Bioactive Small Molecules
  1. Medical Research Areas
  2. GPCR & G Protein
  3. Adenosine Receptor  (腺苷受体)

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