4-(4'-BENZAMIDOANILINO)-6,7-DIMETHOXYQUINAZOLINE HYDROCHLORIDE N-[4-[(6,7-Dimethoxy-4-quinazolinyl)amino]phenyl]benzamide 盐酸盐

CAS 179247-42-8 MFCD09265252

化学结构图

179247-42-8
SMILES: Cl.COC1=CC2N=CN=C(NC3C=CC(=CC=3)NC(=O)C3C=CC=CC=3)C=2C=C1OC

化学属性

Mol. FormulaC23H20N4O3· HCl
Mol. Weight436.89

别名和识别编码

Chemical NameN-[4-[(6,7-Dimethoxy-4-quinazolinyl)amino]phenyl]benzamide hydrochloride
Synonym 4-(4′-Benzamidoanilino)-6,7-dimethoxyquinazoline 盐酸盐 Aurora Kinase Inhibitor II Aurora Kinase Inhibitor II 4-(4'-Benzamidoanilino)-6,7-dimethoxyquinazoline 盐酸盐 Aurora Kinase Inhibitor II 4-(4'-Benzamidoanilino)-6,7-dimethoxyquinazoline 盐酸盐 N-[4-[(6,7-Dimethoxy-4-quinazolinyl)amino]phenyl]benzamide 盐酸盐
MDL NumberMFCD09265252
PubChem Substance ID24724466
CAS Number179247-42-8
Chemical Name TranslationN-[4-[(6,7-Dimethoxy-4-quinazolinyl)amino]phenyl]benzamide 盐酸盐
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分类

  • {SA} Approved Therapeutics/Drug Candidates, AstraZeneca,
  • Approved Therapeutics/Drug Candidates, AstraZeneca, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, DIG-DY, Kinase/Phosphatase Biology, Protein Kinases (PK), Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors
  • {SNA} Approved Therapeutics/Drug Candidates, AstraZeneca, Bioactive Small Molecule Alphabetical Index, DIG-DY, Diversification Ready Pharma-Developed Compounds, Kinase/Phosphatase Biology, Protein Kinases (PK), Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学

相关文献及参考

  • Heron, N.M., et al. , SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors Bioorg. Med. Chem. Lett. 16 , 1320-1323, (2006) 摘要

安全信息

GHS Symbol
WGK Germany3
Signal word Warning
Hazard statements
  • H302 Harmful if swallowed 吞食有害
Hazard Codes Xn
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Risk Statements
  • R22 Harmful if swallowed 吞咽有害

系列性分类

  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Quinazolines 喹唑啉
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Kinase/Phosphatase Biology - Cell Signaling and Neuroscience
  5. Serine/Threonine Kinase Biology - Kinase/Phosphatase Biology
  6. Serine/Threonine Kinase Inhibitors - Serine/Threonine Kinase Biology
  7. Protein Kinases (PK) - Serine/Threonine Kinase Inhibitors

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