(2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-Hydroxy-6-Methyltetrahydro-2H-Pyran-2-Yl)Oxy)-2-Ethyl-3,4,10-Trihydroxy-13-(((2R,4R,5S,6S)-5-Hydroxy-4-Methoxy-4,6-Dimethyltetrahydro-2H-Pyran-2-Yl)Oxy)-3,5,8,10,12,14-Hexamethyl-7-Propyl-1-Oxa-7-Azacyclopentadecan-15-One 加米霉素

CAS 145435-72-9 MFCD09954125

化学结构图

145435-72-9
SMILES: CCCN1C[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(O)C[C@H]1C

化学属性

Mol. FormulaC40H76N2O12
Mol. Weight777.04

别名和识别编码

Chemical Name(2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-Hydroxy-6-Methyltetrahydro-2H-Pyran-2-Yl)Oxy)-2-Ethyl-3,4,10-Trihydroxy-13-(((2R,4R,5S,6S)-5-Hydroxy-4-Methoxy-4,6-Dimethyltetrahydro-2H-Pyran-2-Yl)Oxy)-3,5,8,10,12,14-Hexamethyl-7-Propyl-1-Oxa-7-Azacyclopentadecan-15-One
CAS Number145435-72-9
Synonym (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-Cmethyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy]-1-oxa-7-azacyclopentadecan-15-one GAMITHROMYCIN ######## 加米霉素
Chemical Name Translation加米霉素
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分类

  • Carbohydrates & Derivatives
  • Chiral Reagents
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • A macrolide compound which is known to have antibacterial activity, and is useful in the therapy of bacterial infections in mammals. Antibiotic.

相关文献及参考

  • Broto, P., et al.: Eur. J. Med. Chem., 19, 71 (1984),
  • Farrar, V., et al.: J. Med. Chem., 36, 3517 (1993),
  • Clark, D., et al.: J. Pharm. Sci., 88, 807 (1999),

系列性分类

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