CAS 4635-59-0 MFCD00000754-4-Chlorobutyryl chloride 4-氯丁酰氯 -LabNovo

4-Chlorobutyryl chloride 4-氯丁酰氯

CAS 4635-59-0 MFCD00000754

化学结构图

SMILES: O=C(Cl)CCCCl

化学属性

Mol. Formula	C4H6Cl2O
Mol. Weight	141
Refractive index	1.4600 to 1.4640
Autoignition Point	824 °F
Boiling Point	173-174
Vapor Pressure	3 mmHg ( 20 °C)
Density	1.26
Flash Point	72°C(lit.)
TSCA	Yes
Melting Point	-47°C
Appearance	白色至微黄色、有刺激性的液体。溶于乙醚。
Solubility	溶于乙醚

别名和识别编码

Chemical Name	4-Chlorobutyryl chloride
MDL Number	MFCD00000754
CAS Number	4635-59-0
Beilstein Registry Number	773860
PubChem Substance ID	78370
EC Number	225-059-1
Synonym	4-氯丁基氯 Γ-氯代丁酰氯 4-CHLOROBUTANOYLCHLORIDE Butyryl chloride, 4-chloro- 4-氯代丁酰氯 4-chloro-butanoylchlorid gamma-Chlorobutyroyl chloride 4-CHLOROBUTYRYL CHLORIDE gamma-Chlorobutyryl chloride 4-Chlorobutyrylcy Chloride 4-Chlorobutyrylchloride,98% 4-chloro-butyrylchlorid 4-Chlorobutyric acid chloride R-CHLOROBUTYRYL CHLORIDE Butanoyl chloride, 4-chloro- 4-Chlorobutyroyl chloride 4-Chlorobutyl chloride 4-ChlorobutyrylChloride95% 4-氯丙基氯 4-CHLOROBUTYRIC ACID CHLORIDE 4-Chlorobutyryl chloride 4-CBC gamma-Chloro-n-butyryl chloride -Chlorobutyrylchloride gamma-chlorobutyrylchloride 4-CHLOROBUTYROYL CHLORIDE 对氯丁酰氯 4-Chlorobutanoic acid chloride 4-Chlorobutanoyl chloride 4-CHLOROBUTYRYL CHLORIDE, TECH., 95% γ-氯代丁酰氯 4-氯丁酰氯 gamma-chlorobutyroylchloride
Reaxys-RN	773860
Chemical Name Translation	4-氯丁酰氯
LabNetwork Molecule ID	LN00194775
InChI	InChI=1S/C4H6Cl2O/c5-3-1-2-4(6)7/h1-3H2

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

产品应用

医药农药中间体。

安全信息

GHS Symbol

WGK Germany1

Hazard statements

H227 Combustible liquid 可燃液体
H290 May be corrosive to metals 可能腐蚀金属。
H302 Harmful if swallowed 吞食有害
H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
H330 Fatal if inhaled 吸入致命

Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

RTECSEM1406000

Precautionary statements

P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P284 Wear respiratory protection.? 佩戴呼吸保护装置。
P301+P330+P331
P301+P330+P331+P310
P303+P361+P353
P304+P340+P310
P304+P340+P311
P305+P351+P338
P305+P351+P338+P310
P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
P370+P378
P403+P233
P501 Dispose of contents/container to..… 处理内容物/容器.....

Signal word Danger

Packing GroupII

UN Number 2922 3390 UN2927

Risk Statements

R22 Harmful if swallowed 吞咽有害
R23 Toxic by inhalation 吸入有毒
R29 Contact with water liberates toxic gas. 遇水释放出有毒气体
R35 Causes severe burns 会导致严重灼伤

Safety Statements

S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；

Storage condition Moisture Sensitive

Hazard Codes 6.1 T T,C

Hazard Class8/6.1

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 650 mg/m3/4H
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - respiratory depression
   Skin and Appendages - hair
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0570772

其他信息

蒸气压:3 mm Hg ( 20 °C)
用途一:用作医药中间体，用于生产氟哌啶醇、三氯哌丁苯等
海关编码:29159080
TCI Shanghai:4-氯丁酰氯 4-Chlorobutyryl Chloride,>;98.0%(GC)(4635-59-0)
MOL 文件:4635-59-0.mol
方法二:由γ-丁内酯经氯化而得。将γ-丁内酯和氯化锌搅拌升温，在55-60℃下反应1h。于60℃慢慢加入氯化亚砜，反应2h。在5-6h内升温至80℃。静置过夜，取上部清液常压蒸馏后再重蒸1次，收集馏分得4-氯丁酰氯。
Acros Organics:4-氯丁酰氯 4-Chlorobutyryl chloride, 98%(4635-59-0)
存储注意事项:湿度敏感
下游产品:特非那定 --> 环丙甲酸 --> 左乙拉西坦 --> 4-氯苯基环丙基甲基酮
敏感性:Moisture Sensitive
方法一:其制备方法是将丁内酯、无水氯化锌和氯化亚砜置于反应瓶中，于55℃搅拌12h，减压蒸馏收集产品。
MSDS 信息:4-CBC(4635-59-0).msds
和水反应。
Alfa Aesar:4-氯丁酰氯,98% 4-Chlorobutyryl chloride, 98%(4635-59-0)
上游原料:氯化锌 --> gamma-丁内酯
4-氯丁酰氯价格(试剂级):更新日期产品编号产品名称包装价格 2014/06/02 C0824 4-氯丁酰氯 4-Chlorobutyryl Chloride 500ML 1040元 2014/06/02 C0824 4-氯丁酰氯 4-Chlorobutyryl Chloride 25ML 178元 2010/06/21 108900010 4-氯丁酰氯 4-Chlorobutyryl chloride 98% 1 LT 2664元
Sigma Aldrich:4635-59-0(sigmaaldrich)
Hazard Note:Toxic/Corrosive/Moisture Sensitive
用途二:γ-氯代丁酰氯是植物生长调节剂抗倒酯的中间体，也是医药氟哌啶醇的中间体。