1,1,2,2-Tetrachloroethane 1,1,2,2-四氯乙烷

CAS 79-34-5 MFCD00000848

化学结构图

79-34-5
SMILES: ClC(Cl)C(Cl)Cl

化学属性

Mol. FormulaC2H2Cl4
Mol. Weight167.85
Density1.586
Refractive index1.4930 to 1.4970
Vapor Density5.8 (vs air)
Boiling Point147
Vapor Pressure8 mmHg ( 20 °C)
Melting Point-43
TSCAYes
Solubility0.3 G/100 ML (25 ºC)
Flash Point142-146°C
Stability对光敏感

别名和识别编码

Chemical Name1,1,2,2-Tetrachloroethane
Synonym 1,1,2,2-Tetrachloroethane {LY} 1,1,2,2-Tetrachloroethane 1,1,2,2-czterochloroetan(polish) 1,1,2,2-tce 1,1,2,2-tetrachlorethan 1,1,2,2-tetrachloroethane 1,1,2,2-四氯乙烷, 98+% 1.1.2.2-四氯乙烷 sym-tetrachloroethane Acetosol Acetylene tetrachloride Bonoform F 130 (halocar NCI-C03554 RCRA waste number U209 TCE Tetrachlorethane ethane, 1,1,2,2-tetrachloro- freon 130 s-Tetrachloroethane {} {LY} 1,1,2,2-Tetrachloroethane {} {} {LY} 1,1,2,2-Tetrachloroethane {} {} {} {LY} 1,1,2,2-Tetrachloroethane {} {} {} {} {LY} 1,1,2,2-Tetrachloroethane {} {} {} {} {} {LY} 1,1,2,2-Tetrachloroethane {} {} {} {} {} {} {LY} 1,1,2,2-Tetrachloroethane {} {} {} {} {} {} {} {LY} 1,1,2,2-Tetrachloroethane {} {} {} {} {} {} {} {} {} {} {} {} {} {}
CAS Number79-34-5
EC Number201-197-8
Beilstein Registry Number969206
MDL NumberMFCD00000848
Merck Number9189
PubChem Substance ID6591
Chemical Name Translation1,1,2,2-四氯乙烷
Reaxys-RN969206
Wiswesser Line NotationGYGYGG
LabNetwork Molecule IDLN00194710
InChIInChI=1S/C2H2Cl4/c3-1(4)2(5)6/h1-2H
Canonical SMILESClC(Cl)C(Cl)Cl
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分类

  • {SNA} Alpha Sort, Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Chemical Class, Chloro, Chromatography, Environmental Standards, Halogenated, T, T-Z, TA - TE, Volatiles/ Semivolatiles
  • {SNA} ACS and Reagen
  • {SNA} Additional Standards, Alpha Sort, Analytical Standards, Chemical Class, Chloro, Chromatography, Environmental Standards, Halogenated, Organic Pollutant Standards, T-Z, Volatiles & Semivolatiles, Volatiles/ Semivolatiles, 分析/色谱

产品应用

  • 溶剂。测折光率。结晶学上用作浸液。生物实验上用于使肾、肝和肠胃道病变。涂料去锈剂。可可豆中测定可可碱。�

相关文献及参考

  • Short: II/27B
  • Merck: 14,9189
  • Short: II/5
  • Merck: 14,9189 Beilstein: 1,IV,144
  • Short: III/31a

安全信息

Signal word Danger
GHS Symbol
WGK Germany3
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S38 In case of insufficient ventilation wear suitable respiratory equipment 通风不良时,佩带适当的呼吸器;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
Risk Statements
  • R26/27 Very toxic by inhalation and in contact with skin 吸入及皮肤接触都有剧毒
  • R51/53
Precautionary statements
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P302+P350
  • P302+P352+P310
  • P302+P352+P332+P313+P362+P364
  • P303+P361+P353
  • P304+P340+P310
  • P305+P351+P338
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P332+P313
  • P337+P313
  • P361+P364
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H301+H331
  • H330 Fatal if inhaled 吸入致命
  • H310 Fatal in contact with skin 皮肤接触致命
  • H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSKI8575000
Packing GroupII
UN Number 1702 UN 1702 6.1/PG 2
Hazard Codes 6.1 T+,N
Storage condition 2-8°C {LY} 2-8°C Refrigerator {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C
Hazard Class6.1
Warnings 危化品目录(2015)
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 42 gm/kg/78W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-27,1978

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 110 gm/kg/78W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-27,1978

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 55 gm/kg/78W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-27,1978

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Liver - hepatitis (hepatocellular necrosis), zonal
   Behavioral - sleep
   Liver - fatty liver degeneration
REFERENCE :
   AJHYA2 American Journal of Hygiene.  (Baltimore, MD)  V.1-80, 1921-64.  For
   publisher information, see AJEPAS.  Volume(issue)/page/year: 16,325,1932

TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1000 ppm/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JIHTAB Journal of Industrial Hygiene and Toxicology.  (Cambridge, MA)
   V.18-31, 1936-49.  For publisher information, see AEHLAU.
   Volume(issue)/page/year: 31,343,1949

{hazard_com

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Human
DOSE/DURATION           : 1000 mg/m3/30M
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - hallucinations, distorted perceptions
REFERENCE :
   AHBAAM Archiv fuer Hygiene und Bakteriologie.  (Munich, Fed. Rep. Ger.)
   V.101-154, 1929-71.  For publisher information, see ZHPMAT.
   Volume(issue)/page/year: 116,131,1936

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   QJPPAL Quarterly Journal of Pharmacy & Pharmacology.  (London, UK)  V.2-21,
   1929-48.  For publisher information, see JPPMAB.  Volume(issue)/page/year:
   7,205,1934

TYPE OF TEST

{hazar

TYPE OF TEST            : Sex chromosome loss and nondisjunction
TEST SYSTEM             : Mold - Aspergillus nidulans
DOSE/DURATION           : 200 ppm
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 201,401,1988

TYPE OF TEST            : Mutation test systems - not otherwise specified
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 343,157,1995

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 10 ug/plate
REFERENCE :
   TECSDY Toxicological and Environmental Chemistry.  (Gordon & Breach Science
   Pub. Inc., 1 Park Ave., New York, NY 10016)  V.3(3/4)-    1981-
   Volume(issue)/page/year: 15,101,1987

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 56 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Li

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human HeLa cell
DOSE/DURATION           : 6 mmol/L
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 13,2389,1992

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 56 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   10(Suppl 10),1,1987

TYPE OF

Restrict 危险品

其他信息

  • color:slightly green-yellow
  • 下游产品:氯乙酸 --> 三氯乙烯 --> 硫光气 --> 六氯乙烷 --> 4-氯甲基苯乙烯 --> 十溴二苯醚 --> 五氯乙烷
  • MSDS 信息:1,1,2,2-四氯乙烷(79-34-5).msds
  • Sigma Aldrich:79-34-5(sigmaaldrich)
  • Acros Organics:1,1,2,2-四氯乙烷 1,1,2,2-Tetrachloroethane, 98.50%(79-34-5)
  • 方法一:由乙炔氯化制得。反应在四氯乙烷本身为溶剂下进行(气态乙炔和氯直接反应会发生爆炸),催化剂为五氯化锑或三氯化铁。当采用三氯化铁催化剂时,使系统保持负压,四氯乙烷处天回流状态,连续通入干燥的乙炔和氯气,反应热由回流的四氯乙烷蒸气吸收移走,收率为97%(对乙炔)。
  • Alfa Aesar:1,1,2,2-四氯乙烷,98+% 1,1,2,2-Tetrachloroethane, 98+%(79-34-5)
  • 用途二:用作溶剂及分析试剂
  • 能与乙醇、甲醇、乙醚、氯仿、苯、四氯化碳、二硫化碳、石油醚、二甲基甲酰胺及油类混溶,难溶于水。能随水蒸气挥发,有氯仿气味,不燃烧。水中溶解度:
  • 急性毒性:口服-大鼠LD50: 250 毫克/公斤;腹腔-小鼠 LD50: 821 毫克/公斤
  • 灭火剂:泡沫、干粉、砂土
  • 挥发性有机化合物(VOCs)单组分标准液
  • 1,1,2,2-四氯乙烷价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80123118 四氯乙烷 500ml 32.4元 2011/08/23 80123128 四氯乙烷 500ml 27.1元 2011/08/23 40057361 四氯乙烷 5ml 27.1元
  • 能与乙醇、甲醇、乙醚、氯仿、苯、四氯化碳、二硫化碳、石油醚、二甲基甲酰胺及油类混溶,难溶于水。能随水蒸气挥发,有氯仿气味,不燃烧。
  • 类别:农药
  • 用途四:用于有机合成。工业上用于生产金属净洗剂、杀虫剂、除草剂、溶剂等.校准仪器和装置;评价方法;工作标准;质量保证/质量控制;其他。
  • 职业标准:TWA 35 毫克/立方米; STEL 35 毫克/立方米
  • 用途一:用于生产金属净洗剂、杀虫剂、除草剂、溶剂等
  • 储运特性:库房通风低温干燥; 与氧化剂、食品添加剂分开存放
  • 可燃性危险特性:不易燃; 接触氢氧化钾加热放出易燃气体;水可促分解; 燃烧释放有毒氯化物烟雾
  • TCI Shanghai:1,1,2,2-四氯乙烷(1mg/ml的甲醇溶液)[用于水分析] 1,1,2,2-Tetrachloroethane (1mg/ml in Methanol) [for Water Analysis](79-34-5)
  • MOL 文件:79-34-5.mol
  • 上游原料:三氯化铁 --> 五氯化锑
  • 毒性分级:高毒
  • 用途三:该品是有效的溶剂。但因毒性大,使这方面的用途受到限制。工业中主要用作三氯乙烯、四氯乙烯的原料。
  • 外观性质:无色液体,有氯仿样的气味。
  • 爆炸物危险特性:遇钠或钾可爆炸
  • 蒸气密度:5.8 (vs air)
  • 蒸气压:8 mm Hg ( 20 °C)

系列性分类


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