1,1,2-Trichloroethane 1,1,2-三氯乙烷

CAS 79-00-5 MFCD00000852

化学结构图

79-00-5
SMILES: ClCC(Cl)Cl

化学属性

Mol. FormulaC2H3Cl3
Mol. Weight133.40
Boiling Point114°C
Refractive index1.4700 to 1.4720
Density1.435
Stability对光敏感
Melting Point-37°C
Flash Point11°C
Solubility4 g/L (20 °C)

别名和识别编码

Chemical Name1,1,2-Trichloroethane
Synonym 1,1,2-Trichloroethane {LY} 1,1,2-Trichloroethane 1,1,2-tce 1,1,2-trichloro-ethan 1,1,2-三氯乙烷 1,1,2-三氯乙烷;三氯化乙烷;β-三氯乙烷 1,2,2-Trichloroethane 1,1,2-三氯乙烷 1,1,2-三氯乙酸酯 2-三氯乙烷 CHCl2CH2Cl Ethane trichloride Ethane,1,1,2-trichloro- NCI-C04579 R-140 RCRA waste number U227 RCRA waste number U359 Trichloroethane Trichloroethane, 1,1,2-Vinyl trichloride Trichloräthan Trojchloroetan(1,1,2) VINYL TRICHLORIDE Vinyl trichloride Vinyl trichloride,β-Trichloroethan b beta-T {} {LY} 1,1,2-Trichloroethane {} {} {LY} 1,1,2-Trichloroethane {} {} {} {LY} 1,1,2-Trichloroethane {} {} {} {} {LY} 1,1,2-Trichloroethane {} {} {} {} {} {LY} 1,1,2-Trichloroethane
MDL NumberMFCD00000852
CAS Number79-00-5
PubChem Substance ID87576342
Beilstein Registry Number1,85
EC Number201-166-9
Chemical Name Translation1,1,2-三氯乙烷
Reaxys-RN1731726
Merck Number9637
Wiswesser Line NotationGYG1G
LabNetwork Molecule IDLN00194303
Canonical SMILESClC(Cl)CCl
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分类

  • {SNA} Additional Standards, Alpha Sort, Analytical Standards, Chemical Class, Chloro,
  • {SA} Alkyl, Building Blocks, Chemical Synthesis, Halogenated Hydrocarbons, Organic Building Blocks
  • {uni_hamburg} no charge; 2fragments
  • {SNA} Alpha Sort, Alphabetical Index of Analytical Standards, Analytical Standards, Chemical Class, Chloro, Chromatography, Environmental Standards, Halogenated, Standards for Personal Care and Cosmetic Products, T, T-Z, TP - TZ, Volatiles/ Semivolatiles, neats, prohibited substances (EU-REGULATION No 1223/2009), 分析/色谱

产品应用

  • 脂肪、油脂、树脂、生物碱等溶剂,有机合成。

相关文献及参考

  • Short: III/20a
  • Short: IV/1a
  • Merck: 14,9637 Beilstein: 1,IV,139
  • Merck: 14,9637
  • Short: III/20c

安全信息

Precautionary statements
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P332+P313
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P301+P312+P330
  • P302+P350
  • P337+P313
  • P302+P352+P332+P313+P362+P364
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P303+P361+P353
  • P403+P233
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P305+P351+P338+P337+P313
  • P308+P311
  • P405 Store locked up. 上锁保管。
  • P304+P340+P311
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
WGK Germany3
Signal word Danger
Hazard statements
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H332 Harmful if inhaled 吸入有害
  • H351 Suspected of causing cancer 怀疑致癌
  • H302 Harmful if swallowed 吞食有害
  • H312 Harmful in contact with skin 皮肤接触有害
  • H302+H312
  • H331 Toxic if inhaled 吸入中毒
  • H412 Harmfutoaquaticlifewithlonglastingeffects 对水生生物有害并具有长期影响。
GHS Symbol
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSKJ3150000
Safety Statements
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S9 Keep container in a well-ventilated place 保持容器在通风良好的场所;
  • S46 If swallowed, seek medical advice immediately and show this container or label 食入时,立即求医并出示容器/标签;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Hazard Codes T Xn
Risk Statements
  • R11 Highly flammable 非常易燃
  • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
  • R39/23/24/25 Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed 毒性:吸入,皮肤接触和吞食都会产生十分严重的不可逆危险
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
  • R66 Repeated exposure may cause skin dryness or cracking 反复接触可能导致皮肤干燥或皴裂
UN Number 2810
Packing GroupIII
Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
Hazard Class6.1
Warnings 危化品目录(2015) 危险化学品
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 76 gm/kg/78W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
   Endocrine - adrenal cortex tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-74,1978

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 152 gm/kg/78W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
   Endocrine - adrenal cortex tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-74,1978

{h

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Behavioral - sleep
   Liver - hepatitis (hepatocellular necrosis), zonal
REFERENCE :
   AJHYA2 American Journal of Hygiene.  (Baltimore, MD)  V.1-80, 1921-64.  For
   publisher information, see AJEPAS.  Volume(issue)/page/year: 16,325,1932

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 836 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TSCAT* Office of Toxic Substances Report.  (U.S. Environmental Protection
   Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460)
   Volume(issue)/page/year: OTS051

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 3730 uL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   30,470,1969

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 970 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AOHYA3 Annals of Occupational Hygiene.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford,

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 135 mmol/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11

TYPE OF TEST            : Micronucleus test
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 100 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(iss

TYPE OF TEST            : Sex chromosome loss and nondisjunction
TEST SYSTEM             : Mold - Aspergillus nidulans
DOSE/DURATION           : 750 ppm
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 201,401,1988

TYPE OF TEST            : Morphological transformation
TEST SYSTEM             : Rodent - mouse Embryo
DOSE/DURATION           : 25 mg/L
REFERENCE :
   CALEDQ Cancer Letters (Shannon, Ireland).  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1975- Volume(issue)/page/year:
   28,85,1985

TYPE OF TEST            : DNA adduct
TEST SYSTEM             : Mammal - species unspecified Lymphocyte
DOSE/DURATION           : 1 mmol/L
REFERENCE :
   TOLED5 Toxicology Letters.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1977-  Volume(issue)/page/year: 11,243,1982

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Administration onto the skin
TEST SYSTEM             : Rodent - guinea pig
DOSE/DURATION           : 2880 ug/kg
REFERENCE :
   APTOA6 Acta Pharmacologica et Toxicologica.  (Copenhagen, Denmark)  V.1-59,
   1945-86.  For publisher information, see PHTOEH  Volume(issue)/page/year:
   41,298,1977

TYPE OF TEST            : Mut

其他信息

  • 下游产品:二氯乙烯 --> 1,1-二氯乙烯
  • 可燃性危险特性:不易燃; 燃烧产生有毒
  • 储运特性:库房通风低温干燥; 与食品添加剂分开存放
  • {A
  • 图谱信息:1,1,2-三氯乙烷(79-00-5)Raman光谱 1,1,2-三氯乙烷(79-00-5)核磁图( 1 HNMR) 1,1,2-三氯乙烷(79-00-5)红外图谱(IR1) 1,1,2
  • 方法一:1.氯乙烯氯化法预先往反应釜内投入三氯乙烷,然后于20-25℃下通入氯乙烯和氯气(摩尔比1:1.2)进行氯化合成。生成物经水洗、分离而得。2.1,2-二氯乙烷氯化法在三氯化铝或其他金属氯化物存在下,于60℃氯化即得。
  • Hazard Note:Irritant
  • 用途一:主要用作脂肪、树脂、蜡、生物碱的溶剂,橡胶和树脂的中间体,农药杀虫剂,制备1,1-二氯乙烯等化学品
  • 用途四:脂肪、油脂、树脂、生物碱等溶剂,有机合成。
  • {Chemi
  • 有愉快的气味。不燃烧。溶于乙醇、乙醚和
  • 刺激数据:皮肤-兔子 810 毫克/24小时 重度; 眼睛-兔子500 毫克/24小时 轻度
  • 用途二:用于有机合成,也用作醋酸纤维和橡胶的溶剂
  • 急性毒性:腹腔-大鼠 LD50: 265 毫克/公斤; 口服-小鼠 LD50: 378 毫克/公斤
  • 挥发性有机化合物(VOCs)单组分标准液
  • 用途五:脂肪、油脂、树脂、生物碱等溶剂,有机合成。校准仪器和装置;评价方法;工作标准;质量保证/质量控制;其他。
  • 用途三:用作脂肪、油、蜡和树脂的溶剂,染料、香料的萃取剂,树脂和橡胶等的中间体,农业上的杀虫剂、熏蒸剂以及合成1,1-二氯乙烯的原料。用于生产偏二氯乙烯。
  • 防护措施:高毒。对眼、鼻粘膜有刺激作用。小鼠吸入4小时,其LD50为0.002。吸入3小时,其LD50为0.018。经口LD50为0.1~0.2g/kg。空气中最高容许浓度10ppm。
  • 类别:农药
  • 图谱信息:1,1,2-三氯乙烷(79-00-5)Raman光谱 1,1,2-三氯乙烷(79-00-5)核磁图( 1 HNMR) 1
  • 1,1,2-三氯乙烷价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80133328 1.1.2-三氯乙烷 500ml 28.4元 2011/04/16 T0381 1,1,2-三氯乙烷 1,1,2-Trichloroethane 25G 146元 2011/04/16 S0640 1,1,2-三氯乙烷(1mg/ml的甲醇溶液)[用于水分析] 1,1,2-Trichloroethane (1mg/ml in Methanol) [for Water Analysis] 1ML 198元
  • TCI Shanghai:1,1,2-三氯乙烷(1mg/ml的甲醇溶液)[用于水分析] 1,1,2-Trichloroethane (1mg/ml in Methanol) [for Water Analysis](79-00-5)
  • Acros Organics:1,1,2-三氯乙烷 1,1,2-Trichloroethane, 98%(
  • Sigma Aldrich:79-00-5(sigmaaldrich)
  • 上游原料:1,2-二氯乙烷 --> 三氯乙烷
  • 常规方法:用耐酸铁桶包装。
  • 毒性分级:高毒
  • 职业标准:TWA 45 毫克/立方米; STEL 110 毫克/立方米
  • MOL 文件:79-00-5.mol
  • MSDS 信息:1,1,2-三氯乙烷(79-00-5).msds
  • 外观性质:无色液体,有芳香气味。
  • Acros Organics:1,1,2-三氯乙烷 1,1,2-Trichloroethane, 98%(79-00-5)

系列性分类


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