(Dimethylamino)Acetonitrile (剧毒品,不能销售)(二甲氨基)乙腈

CAS 926-64-7 MFCD00001890

化学结构图

926-64-7
SMILES: CN(C)CC#N

化学属性

Mol. FormulaC4H8N2
Mol. Weight84.14
Refractive index1.4100
Boiling Point137-138°
Density0.863
Flash Point36°(96°F)
TSCANo
Vapor Pressure760 mmHg ( 137 °C)
Solubility可溶

别名和识别编码

Chemical Name(Dimethylamino)Acetonitrile
Synonym DIMETHYLCYANOCACETAMIDE N,N-Dimethylaminoacetonitrile (Dimethylamino)acetonitrile 2-(二甲胺基)乙腈 (CH3)2NCH2CN N,N-DIMETHYLGLYCINONITRILE N,N-二甲基氨基乙腈 N,N-Dimethylglcinonitril N-(Cyanomethyl)dimethylamine dimethylamino-acetonitrile N,N-二甲氨基乙腈 Dimethylaminoacetonitrile N,N-甲基氨基乙腈 2-Dimethylaminoacetonitrile Cyantrimethylamin n,n-dimethyl-glycinonitril 2-(二甲氨基)乙腈 N,N-Dimethylglycinonitrile dimethylaminoacetonitrile N,N-二甲胺基乙氰 DIMETHYLAMINOACETONITRITE 2-(DIMETHYLAMINO)ACETRONITRILE DIMETHYLAMINOACETONITRILE Glycinonitrile, N,N-dimethyl- Acetonitrile, (dimethylamino)- (dimethylamino)-acetonitril
CAS Number926-64-7
PubChem Substance ID61237
EC Number213-140-4
Beilstein Registry Number1735677
MDL NumberMFCD00001890
Chemical Name Translation(剧毒品,不能销售)(二甲氨基)乙腈
Wiswesser Line NotationNC1N1&1
InChIInChI=1S/C4H8N2/c1-6(2)4-3-5/h4H2,1-2H3
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分类

  • Building Blocks, C1 to C5, Chemical Synthesis, Cyanides/Nitriles, Nitrogen Compounds, Organic Building Blocks
  • {uni_hamburg} no charge; 1fragment
  • {SA} Building Blocks, C1 to C5, Chemical Synthesis, Cyanides/Nitriles, Nitrogen Compounds, Organic Building Blocks
  • {SNA} Building Blocks, C1 to C5, Chemical Synthesis, Cyanides/Nitriles, Nitrogen Compounds, Organic Building Blocks

相关文献及参考

  • Beil. 4 ,IV,2368
  • Aldrich MSDS 1 , 742:D / Corp MSDS 1 (1), 1329:D / RegBook 1 (1), 1005:M / Sax 6 , 1108 / Structure Index 1 , 157:B:2 / Vapor Phase 3 , 814:C
  • Short: III/38B Title: Refractive Indices of Organic Liquids Author: Wohlfarth, Ch.; Wohlfarth, B. Editor: Lechner, M.D. Source: Landolt-Börnstein, New Series Volume: III/38B Year: 1996 Keyword: organic compounds; refractive index; liquids ISBN: 3-540-60596-7 ISBN: 978-3-540-60596-6 Internet Resource: DOI:10.1007/b85533 RefComment: VII, 4210 pages, Hardcover Abstract: Volume III/38 Optical Constants provides critically evaluated data on refractive indices of inorganic and organic liquids and their wavelength dependence (dispension). Part A contains the inorganic, organometallic, and organononmetallic liquids, and the binary liquid mixtures (about 900 pure substances and their mixtures). Part B contains data of more than 7600 organic liquids.
  • Short: EINECS Title: EINECS (European Inventory of Existing Commercial Chemical Substances) Source: Official Journal of the European Communities Volume: C 146 A (15.06.1990) Page: 1 Year: 1990 Internet Resource: http://ecb.jrc.ec.europa.eu/esis/index.php?PGM=ein Publish_Date: 1990/06/15
  • Formyl anion equivalent. Self-condensation was found to compete with alkylation in the Stork LDA procedure, but the molecule was successfully used to introduce a formyl group by SN2' alkylation in the presence of K2CO3, in a synthesis of -cyclocitral: Tetrahedron Lett., 25, 3457 (1984):
  • For a review of the use of ɑ-dialkylaminonitriles as acyl anion equivalents, see: Tetrahedron, 39, 3207 (1983).

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H310 Fatal in contact with skin 皮肤接触致命
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H300 Fatal if swallowed 吞食致命
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Hazard Codes T+
RTECSAL9450000
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P301+P310
  • P302+P350
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+P351+P338
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
Signal word Danger
UN Number UN2378 2378 UN 2378 3/PG 2
Risk Statements
  • R27 Very toxic in contact with skin 与皮肤接触极毒
  • R25 Toxic if swallowed 吞咽有毒
  • R36 Irritating to eyes 刺激眼睛
  • R10 Flammable 易燃
  • R23/25 Toxic by inhalation and if swallowed 吸入及吞食都有毒
Safety Statements
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S38 In case of insufficient ventilation wear suitable respiratory equipment 通风不良时,佩带适当的呼吸器;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
Packing GroupII
Hazard Class6.1
Storage condition Flammables area
Restrict 剧毒化学品
Warnings 危化品目录(2015) 危险化学品
TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 250 ppm/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   23,95,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   23,95,1962

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Ocular
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - conjunctive irritation
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
REFERENCE :
   EPASR* United States Environmental Protection Agency, Office of Pesticides
   and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW,
   Washington, DC 20460)  History unknown.  Volume(issue)/page/year:
   FYI-OTS-0483-0238

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 32 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.

其他信息

  • 可燃性危险特性:易燃; 高热放出有毒氮氧化物气体
  • Alfa Aesar:二甲氨基乙腈,98% Dimethylaminoacetonitrile, 98%(926-64-7)
  • 刺激数据:皮肤-兔子 500 毫克/24小时 轻度; 眼睛-兔子 20 毫克/24小时 中度
  • 储运特性:库房通风低温干燥; 与氧化剂, 酸类分开储运
  • 毒性分级:剧毒
  • Sigma Aldrich:926-64-7(sigmaaldrich)
  • 灭火剂:干粉, 二氧化碳, 砂土, 泡沫
  • 蒸气压:760 mm Hg ( 137 °C)
  • MSDS 信息:N,N-二甲基氨基乙腈(926-64-7).msds
  • 类别:易燃液体
  • 急性毒性:口服-大鼠 LD50: 50 毫克/公斤; 吸入-大鼠 LCL0: 250 PPM/4小时
  • 海关编码:29269095
  • 外观性质:无色至淡黄色液体。
  • MOL 文件:926-64-7.mol
  • 图谱信息:N,N-二甲基氨基乙腈(926-64-7)核磁图( 1 HNMR) N,N-二甲基氨基乙腈(926-64-7)红外图谱(IR1) N,N-二甲基氨基乙腈(926-64-7)质谱(MS) N,N-二甲基氨基乙腈(926-64-7)核磁图( 13 CNMR)
  • N,N-二甲基氨基乙腈价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2010/06/21 211490250 N,N-二甲基氨基乙腈 Dimethylaminoacetonitrile 98% 25 GR 512元
  • Acros Organics:Dimethylaminoacetonitrile,98%(926-64-7)
  • 爆炸物危险特性:蒸气与空气混合可爆

系列性分类


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